Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598302 | 0.83 | LMNA (0.40) | LMNAMAPTALOX12TP53SMN1; SMN2 | |
| SCHEMBL11600611 | 0.83 | LMNA (0.40) | LMNAMAPTALOX12TP53SMN1; SMN2 | |
| SCHEMBL6075249 | 0.83 | ESR1 (0.42) | LMNAMAPTTP53ALDH1A1CYP3A4 | |
| SCHEMBL29388293 | 0.83 | ESR1 (0.42) | LMNAMAPTTP53ALDH1A1CYP3A4 | |
| SCHEMBL11600628 | 0.82 | ALDH1A1 (0.51) | LMNAMAPTALOX12TP53SMN1; SMN2 | |
| SCHEMBL11598499 | 0.82 | ALDH1A1 (0.51) | LMNAMAPTALOX12TP53SMN1; SMN2 | |
| SCHEMBL8999593 | 0.81 | TYR (0.41) | LMNAMAPTALOX12TP53SMN1; SMN2 | |
| SCHEMBL24003140 | 0.80 | TDP1 (0.43) | LMNAALOX12TP53SMN1; SMN2TDP1 | |
| SCHEMBL24776199 | 0.76 | SPHK1 (0.50) | LMNATP53SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL10178491 | 0.76 | HTR2A (0.39) | LMNAMAPTALOX12TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |