SCHEMBL11601249

SCHEMBL11601249

O=C=Nc1ccc(Br)c(N=C=O)c1Br

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.38
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4285629 0.83 CYP3A4 (0.40) CYP3A4ALDH1A1HPGDTDP1TRPA1
SCHEMBL9303930 0.76 CYP3A4 (0.41) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL2169198 0.75 CYP3A4 (0.52) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL5577120 0.74 CYP3A4 (0.48) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL2291859 0.73 CYP3A4 (0.60) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL10659642 0.73 GABRA1 (0.35) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL10841494 0.73 GABRA1 (0.50) CYP3A4GABRA1GABRB2TDP1
SCHEMBL10316767 0.72 CYP3A4 (0.39) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL943420 0.71 CYP3A4 (0.38) CYP3A4GABRA1GABRB2ALDH1A1HPGD
SCHEMBL5786288 0.69 CYP3A4 (0.41) CYP3A4GABRA1GABRB2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4130546-A EPOXY, ISOCYANATE, CURING AGNET, MODIFIED BUTADIENE POLYMER HITACHI CHEMICAL COMPANY, LTD. (JP) 1978-12-19 US disclosed
US-4128531-A EPOXY, ISOCYANATE, CURING AGENT, HYDROXYLATED BUTADIENE POLYMER HITACHI CHEMICAL COMPANY, LTD. (JP) 1978-12-05 US disclosed