Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601249 | 0.83 | CYP3A4 (0.38) | CYP3A4ALDH1A1HPGDTDP1TRPA1 | |
| SCHEMBL9303930 | 0.79 | CYP3A4 (0.41) | CYP3A4ALDH1A1HPGDTDP1TRPA1 | |
| SCHEMBL943420 | 0.78 | CYP3A4 (0.38) | CYP3A4ALDH1A1HPGDTDP1TRPA1 | |
| SCHEMBL11679582 | 0.77 | CYP3A4 (0.35) | CYP3A4ALDH1A1HPGDTDP1TRPA1 | |
| SCHEMBL4284583 | 0.77 | ALDH1A1 (0.36) | CYP3A4ALDH1A1HPGDTDP1 | |
| SCHEMBL2291859 | 0.76 | CYP3A4 (0.60) | CYP3A4ALDH1A1HPGDTDP1TRPA1 | |
| SCHEMBL10316767 | 0.76 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDTDP1TRPA1 | |
| SCHEMBL27633342 | 0.73 | TSHR (0.47) | CYP3A4TSHR | |
| SCHEMBL5786288 | 0.72 | CYP3A4 (0.41) | CYP3A4ALDH1A1HPGDTDP1TRPA1 | |
| SCHEMBL2156211 | 0.71 | CYP3A4 (0.53) | CYP3A4ALDH1A1HPGDTDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203877-A1 | X-RAY-DENSE CONJUGATE | EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKLINKUM | 2009-08-13 | — | — | US | disclosed |
| EP-2046392-A2 | RADIODENSE CONJUGATE | Eberhard-Karls-Universität Tübingen Universitätsklinikum (DE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012102-A2 | RADIODENSE CONJUGATE | EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKLINIKUM (DE) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203877-A1 | X-RAY-DENSE CONJUGATE | FCGR3B, KLK3, XPA | CYP3A4 2608/4885ALDH1A1 2704/4885HPGD 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.