Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10777119 | 0.88 | ADRA1A (0.55) | KDM4EGLAALDH1A1HPGDKMT2A | |
| SCHEMBL11168970 | 0.82 | ADRA1A (0.47) | KDM4EGLAALDH1A1HPGDKMT2A | |
| SCHEMBL2707530 | 0.82 | KDM4E (0.66) | KDM4EGLAALDH1A1KMT2ALMNA | |
| SCHEMBL11800788 | 0.81 | KDM4E (0.46) | KDM4EGLAALDH1A1HPGDKMT2A | |
| SCHEMBL11795717 | 0.79 | KDM4E (0.45) | KDM4EGLAALDH1A1HPGDKMT2A | |
| SCHEMBL1203726 | 0.78 | TSHR (0.61) | KDM4EALDH1A1KMT2ALMNAADRA1A | |
| SCHEMBL9716704 | 0.77 | KDM4E (0.49) | KDM4EGLAALDH1A1HPGDKMT2A | |
| SCHEMBL219602 | 0.77 | ADRA1A (0.55) | KDM4EGLAALDH1A1HPGDKMT2A | |
| SCHEMBL690246 | 0.75 | KDM4E (0.53) | KDM4EGLAALDH1A1HPGDKMT2A | |
| SCHEMBL11819594 | 0.75 | KDM4E (0.46) | KDM4EGLAALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4111933-A | PROTECTION OF FUNCTIONAL GROUPS DURING REACTION AND THEIR SUBSEQUENT RESTORATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | disclosed |