SCHEMBL690246

SCHEMBL690246

CC(=O)c1ccccc1NCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
AGTR1 P30556 3/20 0.53
RAB9A P51151 1/20 0.53
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
AKR1C3 P42330 2/20 0.47
AKR1C2 P52895 2/20 0.47
PDK1 Q15118 1/20 0.44
PDK2 Q15119 1/20 0.44
PDK3 Q15120 1/20 0.44
PDK4 Q16654 1/20 0.44
GLA P06280 1/20 0.44
ITGB3 P05106 1/20 0.44
ITGB1 P05556 1/20 0.44
ITGAV P06756 1/20 0.44
ITGA5 P08648 1/20 0.44
POLB P06746 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL10539920 0.98 KDM4E (0.51) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL10536973 0.98 KDM4E (0.51) KDM4EAGTR1RAB9AALDH1A1HPGD
Methylamine SCHEMBL5383831 0.96 AGTR1 (0.50) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL10541374 0.93 KDM4E (0.55) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL10540484 0.92 KDM4E (0.54) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL29620333 0.85 KDM4E (0.71) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL341645 0.85 KDM4E (0.71) KDM4EAGTR1RAB9AALDH1A1HPGD
SCHEMBL6018454 0.84 AGTR1 (0.48) KDM4EAGTR1RAB9AALDH1A1HPGD
Water SCHEMBL7614858 0.83 KDM4E (0.69) KDM4EAGTR1RAB9AALDH1A1HPGD
Methane SCHEMBL2342916 0.83 KDM4E (0.69) KDM4EAGTR1RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3369522-B1 SOLDER PASTE KOKI KK (JP) 2025-01-22 EP claimed
CN-115894143-B Palladium catalyzed double ligand unguided preparation method for deuterated aromatic compound 宁波萃英化学技术有限公司 2024-05-28 CN claimed
CN-115894143-A Palladium-catalyzed double-ligand non-guide preparation method of deuterated aromatic compound 宁波萃英化学技术有限公司 2023-04-04 CN claimed
US-10933495-B2 Solder paste containing solder powder and flux KOKI COMPANY LIMITED (JP) 2021-03-02 US claimed
CN-109494401-B Holographic polymer electrolyte and preparation method and application thereof 华中科技大学 2021-02-09 CN claimed
CN-107544207-B Holographic photopolymer based on thiol olefin click reaction 华中科技大学 2020-06-02 CN claimed
CN-111048976-A Inorganic perovskite quantum dot distributed feedback laser 曲阜师范大学 2020-04-21 CN claimed
CN-110994344-A Organic laser based on holographic polymer dispersed liquid crystal grating 曲阜师范大学 2020-04-10 CN claimed
EP-3369522-A1 FLUX AND SOLDER COMPOSITION Koki Company Limited (JP) 2018-09-05 EP claimed
US-20180147675-A1 Flux and Solder Composition KOKI COMPANY LIMITED (JP) 2018-05-31 US claimed
WO-2005055947-A2 ENLARGEMENT OF MUCOCUTANEOUS OR CUTANEOUS ORGANS AND SITES WITH TOPICAL COMPOSITIONS YU RUEY J (US) 2005-06-23 WO claimed
US-6824786-B2 TOPICAL APPLYING COSMETIC YU RUEY J (US) 2004-11-30 US claimed
EP-1455734-A1 COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES Yu, Ruey J., Dr. (US) 2004-09-15 EP claimed
US-20030108496-A1 Compositions comprising phenyl-glycine derivatives YU RUEY J (US) 2003-06-12 US claimed
WO-2003045338-A1 COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES YU RUEY J (US) 2003-06-05 WO claimed
EP-1019363-B1 PROCESS FOR THE PREPARATION OF AN INORGANIC SALT OF AN OPTICALLY ACTIVE PHENYLGLYCINE DERIVATIVE DSM NV (NL) 2002-08-28 EP claimed
EP-1019363-A1 PROCESS FOR THE PREPARATION OF AN INORGANIC SALT OF AN OPTICALLY ACTIVE PHENYLGLYCINE DERIVATIVE DSM N.V. (NL) 2000-07-19 EP claimed
WO-1998013335-A1 PROCESS FOR THE PREPARATION OF AN INORGANIC SALT OF AN OPTICALLY ACTIVE PHENYLGLYCINE DERIVATIVE DSM N.V. (NL) 1998-04-02 WO claimed
US-5166397-A Process for producing optically active cyclobutylamines NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1992-11-24 US claimed
EP-0266577-A1 An optically active propanone derivative and process for producing the same and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1988-05-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030108496-A1 Compositions comprising phenyl-glycine derivatives GRHPR, ARL1, SUCLG1 KDM4E 2760/4885AGTR1 634/4885RAB9A 2579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.