SCHEMBL11601302

SCHEMBL11601302

CCCN(C(N)=O)C(N)=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.40
CA2 P00918 5/20 0.40
CA9 Q16790 5/20 0.40
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CA1 P00915 7/20 0.36
CA14 Q9ULX7 1/20 0.36
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 2/20 0.33
TP53 P04637 1/20 0.33
FDPS P14324 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
LMNA P02545 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
EPHX1 P07099 1/20 0.31
CTSD P07339 1/20 0.31
FFAR3 O14843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4727561 0.87 CA2 (0.36) CA12CA2CA9TSHRMAPK1
SCHEMBL7468494 0.85 CA2 (0.34) CA12CA2CA9TSHRMAPK1
SCHEMBL20285412 0.83 CA1 (0.44) CA12CA2CA9TSHRCA1
SCHEMBL13760606 0.83 CA2 (0.33) CA12CA2CA9TSHRMAPK1
SCHEMBL27342440 0.83 CA2 (0.33) CA12CA2CA9TSHRMAPK1
SCHEMBL29634978 0.79 ALDH1A1 (0.50) CA2CA1ALDH1A1HPGDTP53
SCHEMBL27534700 0.79 TDP1 (0.39) CA12CA2CA9
SCHEMBL27619106 0.79 ZDHHC20 (0.38) CA12CA2CA9TSHRALDH1A1
SCHEMBL107452 0.77 CA12 (0.52) CA12CA2CA9TSHRMAPK1
SCHEMBL42388 0.77 CA12 (0.52) CA12CA2CA9TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117082975-A Agrochemical composition 诺力昂化学品国际有限公司 2023-11-17 CN disclosed
WO-2013089212-A1 SUBSTITUTED TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME 塩野義製薬株式会社 (JP) 2013-06-20 WO disclosed
US-4111904-A STABILIZATION OF POLYPYRROLIDONE STAMICARBON, B.V. (NL) 1978-09-05 US disclosed