SCHEMBL11601356

SCHEMBL11601356

CCCSC(C(=O)Cc1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 3/20 0.41
POLB P06746 1/20 0.41
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
PKM P14618 1/20 0.40
AKR1B1 P15121 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CHRM1 P11229 1/20 0.40
LMNA P02545 1/20 0.40
PAX8 Q06710 1/20 0.40
TSHR P16473 1/20 0.39
EPHX1 P07099 4/20 0.39
CNR1 P21554 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8443134 0.76 KMT2A (0.51) PKMSMN1; SMN2CHRM1LMNAPAX8
SCHEMBL5986343 0.71 POLB (0.55) CNR2POLBCES2CES1AKR1B1
SCHEMBL5431716 0.71 TSHR (0.52) CNR2POLBCES2CES1AKR1B1
SCHEMBL13074658 0.71 TSHR (0.52) CNR2POLBCES2CES1AKR1B1
SCHEMBL11613937 0.70 POLB (0.49) CNR2POLBCES2CES1AKR1B1
SCHEMBL7635436 0.70 LMNA (0.58) CNR2CES2CES1AKR1B1LMNA
SCHEMBL28577864 0.70 CES1 (0.54) CNR2CES2CES1AKR1B1TSHR
SCHEMBL8419057 0.70 SOAT2 (0.59) LMNAPAX8EPHX1
SCHEMBL9000782 0.70 SOAT2 (0.59) LMNAPAX8EPHX1
SCHEMBL11536485 0.69 SOAT2 (0.46) POLBCES2CES1LMNAPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4119788-A ODORS, FLAVORS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-10-10 US disclosed
US-4107197-A KETONE REACTED WITH SULFURYL CHLORIDE, ALPHA-CHLORO KETONE REACTED WITH ALKALI METAL COMPOUND INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-08-15 US disclosed
US-4097532-A ENHANCING FLAVOR AND AROMA INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-06-27 US disclosed
US-4088697-A 3-PROPYLTHIO-4-HEPTANOL; FOODSTUFF FLAVORS OR ODORANTS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-05-09 US disclosed
US-4083862-A α-Oxy(oxo) sulfides and ethers INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-04-11 US disclosed
US-4061795-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-12-06 US disclosed
US-4061796-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-12-06 US disclosed
US-4055691-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-25 US disclosed
US-4053655-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-11 US disclosed
US-4053654-A Uses of α-oxy(oxo) sulfides and ethers in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-11 US disclosed
US-4045491-A PERFUMES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-08-30 US disclosed
US-4044164-A BERRY, CEREAL, NUT, BROCCOLI, ONION, CITRUS, JASMIN, MILK CARAMEL, GRAPE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-08-23 US disclosed