Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.42 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9000638 | 0.88 | SOAT2 (0.55) | KMT2ACHRM1LMNAPAX8SOAT2 | |
| SCHEMBL5901073 | 0.88 | SOAT2 (0.55) | KMT2ACHRM1LMNAPAX8SOAT2 | |
| SCHEMBL11252374 | 0.84 | KMT2A (0.49) | KMT2ACHRM1PKMLMNAEPHX1 | |
| SCHEMBL283611 | 0.79 | KMT2A (0.62) | KMT2APKMLMNAMEN1SMN1; SMN2 | |
| SCHEMBL11357298 | 0.79 | SMN1; SMN2 (0.44) | KMT2ACHRM1LMNAMEN1SMN1; SMN2 | |
| SCHEMBL1578734 | 0.78 | KMT2A (0.60) | KMT2APKMLMNAMEN1SMN1; SMN2 | |
| SCHEMBL11601356 | 0.76 | CNR2 (0.41) | CHRM1PKMLMNAPAX8EPHX1 | |
| SCHEMBL27864446 | 0.76 | KMT2A (0.58) | KMT2APKMLMNAMEN1SMN1; SMN2 | |
| SCHEMBL9000631 | 0.76 | CYSLTR2 (0.48) | KMT2ALMNAMEN1SOAT2ACAT1 | |
| SCHEMBL10954939 | 0.75 | EPHX1 (0.53) | KMT2ALMNAEPHX1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |