Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27690103 | 0.73 | KMT2A (0.60) | KMT2AMAPTMEN1LMNAALDH1A1 | |
| SCHEMBL28090836 | 0.72 | HDAC1 (0.51) | KMT2AMEN1P2RX7ADORA2AADORA1 | |
| SCHEMBL32674134 | 0.70 | MAPT (0.59) | KMT2AMAPTMEN1P2RX7ADORA2A | |
| SCHEMBL1752087 | 0.69 | P2RX7 (0.53) | KMT2AMEN1P2RX7ALDH1A1KDM4E | |
| SCHEMBL11340678 | 0.69 | KMT2A (0.57) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL30320367 | 0.68 | KMT2A (0.54) | KMT2AMAPTMEN1LMNAALDH1A1 | |
| SCHEMBL2014881 | 0.68 | MEN1 (0.36) | KMT2AMAPTMEN1LMNAP2RX7 | |
| SCHEMBL11214113 | 0.67 | KMT2A (0.45) | KMT2AMAPTMEN1LMNAALDH1A1 | |
| SCHEMBL6399279 | 0.67 | KDM4E (0.56) | KMT2AMEN1LMNAP2RX7ADORA2A | |
| SCHEMBL23354891 | 0.67 | ALDH1A1 (0.52) | KMT2AMAPTMEN1P2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4079063-A | FROM OXIME-HYDRAZONES | CIBA-GEIGY CORPORATION (US) | 1978-03-14 | — | — | US | disclosed |
| US-4035487-A | INSECTICIDES | CIBA-GEIGY CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |