Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602907 | 0.82 | MAPT (0.48) | CYP3A4SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL11601679 | 0.79 | NPC1 (0.41) | TSHRSMN1; SMN2NPC1GAARAB9A | |
| SCHEMBL11599847 | 0.76 | MAPT (0.49) | NPC1GAARAB9AKMT2AALDH1A1 | |
| SCHEMBL28453126 | 0.75 | MEN1 (0.64) | SMN1; SMN2GAAKMT2AALDH1A1MAPT | |
| SCHEMBL30077298 | 0.75 | MEN1 (0.64) | SMN1; SMN2GAAKMT2AALDH1A1MAPT | |
| SCHEMBL145815 | 0.74 | SIRT6 (0.57) | CYP3A4TSHRNPC1SIRT6RAB9A | |
| SCHEMBL25476901 | 0.74 | ALDH1A1 (0.36) | TSHRSMN1; SMN2KMT2AALDH1A1MAPT | |
| SCHEMBL28054095 | 0.73 | TSHR (0.53) | CYP3A4TSHRSMN1; SMN2NPC1SIRT6 | |
| SCHEMBL11602961 | 0.72 | MAPT (0.54) | CYP3A4NPC1RAB9AKMT2AMAPT | |
| SCHEMBL29629307 | 0.72 | GAA (0.40) | TSHRSMN1; SMN2NPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070536-A | Process for the preparation of 4-benzoylpyrazole derivatives | SANKYO COMPANY LIMITED (JA) | 1978-01-24 | — | — | US | disclosed |