Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.67 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylmethane SCHEMBL10394702 | 0.85 | CALM1 (0.92) | CALM1PLA2G10PLA2G2ALMNAIDH1 | |
| Diphenylmethane SCHEMBL8658678 | 0.82 | CALM1 (0.75) | CALM1PLA2G10PLA2G2ALMNAIDH1 | |
| Diphenylmethane SCHEMBL29127396 | 0.82 | CALM1 (0.75) | CALM1PLA2G10PLA2G2ALMNAIDH1 | |
| Diphenylmethane SCHEMBL5607610 | 0.82 | CALM1 (0.75) | CALM1PLA2G10PLA2G2ALMNAIDH1 | |
| Diphenylmethane SCHEMBL3792579 | 0.82 | CALM1 (1.00) | CALM1PLA2G10PLA2G2ALMNAIDH1 | |
| Diphenylmethane SCHEMBL4361124 | 0.82 | CALM1 (1.00) | CALM1PLA2G10PLA2G2ALMNAIDH1 | |
| Diphenylmethane SCHEMBL28172316 | 0.82 | CALM1 (1.00) | CALM1PLA2G10PLA2G2ALMNAIDH1 | |
| Diphenylmethane SCHEMBL14763944 | 0.82 | CALM1 (1.00) | CALM1PLA2G10PLA2G2ALMNAIDH1 | |
| Diphenylmethane SCHEMBL1303 | 0.82 | CALM1 (1.00) | CALM1PLA2G10PLA2G2ALMNAIDH1 | |
| Benzyl Alcohol SCHEMBL8639974 | 0.81 | TSHR (0.74) | CALM1LMNAIDH1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104259-A | Fireproof polyesters from brominated dihydroxy alkoxy-diphenyl sulfones | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1978-08-01 | — | — | US | disclosed |