Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.68 |
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.67 |
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.67 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12877577 | 1.00 | SIRT5 (0.68) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL16144704 | 0.92 | SIRT2 (0.62) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL13449701 | 0.90 | SIRT2 (0.69) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL1160328 | 0.89 | SIRT5 (0.67) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL8079485 | 0.86 | SIRT5 (0.80) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL13325460 | 0.85 | SIRT2 (0.64) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL16250362 | 0.83 | FOLH1 (0.65) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL15871405 | 0.83 | FOLH1 (0.65) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL16782306 | 0.83 | SIRT2 (0.66) | SIRT5SIRT2SIRT1SIRT3 | |
| SCHEMBL17737200 | 0.82 | SIRT2 (0.85) | SIRT5SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012577-A1 | FURAZANOBENZIMIDAZOLES AS PRODRUGS TO TREAT NEOPLASTIC OR AUTOIMMUNE DISEASES | BASILEA PHARMACEUTICA AG (CH) | 2011-02-03 | — | — | WO | disclosed |