SCHEMBL1160233

SCHEMBL1160233

CCC(C)(C)c1ccccc1-c1c(OP(O)O)cc(C(C)(C)CC)c(C(C)(C)CC)c1-c1ccccc1C(C)(C)CC

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
CASP3 P42574 1/20 0.34
RAB9A P51151 1/20 0.34
ATM Q13315 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1160229 0.90 MAPK1 (0.35) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL560864 0.84 NPC1 (0.31) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL1160231 0.84 NPC1 (0.31) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL1160208 0.79 ALDH1A1 (0.33) ALDH1A1
SCHEMBL1241865 0.76 ALDH1A1 (0.33) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL31059274 0.75 MEN1 (0.31) MAPK1SMN1; SMN2MEN1ALDH1A1KMT2A
SCHEMBL1241928 0.73
SCHEMBL561863 0.72 MAPK1 (0.42) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL1159942 0.72 MAPK1 (0.37) MAPK1SMN1; SMN2NPC1LMNACASP3
SCHEMBL561156 0.72 MAPK1 (0.43) MAPK1SMN1; SMN2NPC1LMNACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2804901-B1 POLYOLEFIN COMPOSITIONS FOR FILM, FIBER AND MOLDED ARTICLES SI GROUP SWITZERLAND CHAA GMBH (CH) 2019-09-11 EP claimed
US-9127144-B2 Polyolefin compositions for film, fiber and molded articles ADDIVANT USA LLC (US) 2015-09-08 US claimed
EP-2804901-A1 POLYOLEFIN COMPOSITIONS FOR FILM, FIBER AND MOLDED ARTICLES Addivant Switzerland GmbH (CH) 2014-11-26 EP claimed
WO-2013109818-A1 POLYOLEFIN COMPOSITIONS FOR FILM, FIBER AND MOLDED ARTICLES CHEMTURA CORPORATION (US) 2013-07-25 WO claimed
US-20130190434-A1 Polyolefin Compositions for Film, Fiber and Molded Articles CHEMTURA CORPORATION (US) 2013-07-25 US claimed
EP-2804901-B1 POLYOLEFIN COMPOSITIONS FOR FILM, FIBER AND MOLDED ARTICLES SI GROUP SWITZERLAND CHAA GMBH (CH) 2019-09-11 EP disclosed
EP-2459574-B1 SOLID ALKYLARYL PHOSPHITE COMPOSITIONS AND METHODS FOR MANUFACTURING SAME ADDIVANT SWITZERLAND GMBH (CH) 2018-06-20 EP disclosed
US-9127144-B2 Polyolefin compositions for film, fiber and molded articles ADDIVANT USA LLC (US) 2015-09-08 US disclosed
EP-2804901-A1 POLYOLEFIN COMPOSITIONS FOR FILM, FIBER AND MOLDED ARTICLES Addivant Switzerland GmbH (CH) 2014-11-26 EP disclosed
WO-2013109818-A1 POLYOLEFIN COMPOSITIONS FOR FILM, FIBER AND MOLDED ARTICLES CHEMTURA CORPORATION (US) 2013-07-25 WO disclosed
US-20130190434-A1 Polyolefin Compositions for Film, Fiber and Molded Articles CHEMTURA CORPORATION (US) 2013-07-25 US disclosed
US-8309635-B2 Solid alkylaryl phosphite compositions and methods for manufacturing same CHEMTURA CORPORATION (US) 2012-11-13 US disclosed
EP-2459574-A1 SOLID ALKYLARYL PHOSPHITE COMPOSITIONS AND METHODS FOR MANUFACTURING SAME Chemtura Corporation (US) 2012-06-06 EP disclosed
WO-2011014474-A1 SOLID ALKYLARYL PHOSPHITE COMPOSITIONS AND METHODS FOR MANUFACTURING SAME CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
US-20110028618-A1 Solid alkylaryl phosphite compositions and methods for manufacturing same SI GROUP, INC. 2011-02-03 US disclosed