SCHEMBL560864

SCHEMBL560864

CCC(C)(C)c1ccccc1-c1cc(OP(O)O)c(C(C)(C)CC)c(-c2ccccc2C(C)(C)CC)c1C(C)(C)CC

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1160231 0.90 NPC1 (0.31) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL1160233 0.84 MAPK1 (0.34) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL561586 0.79 ALDH1A1 (0.32)
SCHEMBL1241928 0.75
SCHEMBL1241865 0.75 ALDH1A1 (0.33) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL561863 0.74 MAPK1 (0.42) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL1159942 0.74 MAPK1 (0.37) NPC1LMNAMAPK1CASP3RAB9A
SCHEMBL31059274 0.74 MEN1 (0.31) MAPK1SMN1; SMN2
SCHEMBL1160206 0.74 ALDH1A1 (0.32)
SCHEMBL561906 0.73 PTPN1 (0.33) NPC1LMNAMAPK1CASP3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2459575-B2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2018-07-25 EP claimed
EP-2459575-B1 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2014-12-17 EP claimed
EP-2459575-A2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS Chemtura Corporation (US) 2012-06-06 EP claimed
US-8048946-B2 Hydrolytically stable phosphite compositions CHEMTURA CORPORATION (US) 2011-11-01 US claimed
WO-2011014529-A2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2011-02-03 WO claimed
US-20110028619-A1 Hydrolytically stable phosphite compositions SI GROUP, INC. 2011-02-03 US claimed
EP-2459575-B2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2018-07-25 EP disclosed
EP-2491078-B1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING ADDIVANT SWITZERLAND GMBH (CH) 2016-09-28 EP disclosed
US-20150021523-A1 Processes For Forming Alkylated Aryl Phosphite Compositions From Complex Hydrocarbon Streams ADDIVANT USA LLC (US) 2015-01-22 US disclosed
EP-2459575-B1 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS ADDIVANT SWITZERLAND GMBH (CH) 2014-12-17 EP disclosed
US-8735628-B2 Processes for forming alkylated aryl phosphite compositions from complex hydrocarbon streams ADDIVANT USA LLC (US) 2014-05-27 US disclosed
US-8258214-B2 Polymers with low gel content and enhanced gas-fading CHEMTURA CORPORATION (US) 2012-09-04 US disclosed
EP-2491078-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING Chemtura Corporation (US) 2012-08-29 EP disclosed
WO-2011049728-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING CHEMTURA CORPORATION (US) 2011-04-28 WO disclosed
WO-2011014529-A2 HYDROLYTICALLY STABLE PHOSPHITE COMPOSITIONS CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
WO-2011014351-A1 PROCESS FOR FORMING ALKYLATED ARYL PHOSPHITE COMPOSITIONS FROM COMPLEX HYDROCARBON STREAMS CHEMTURA CORPORATION (US) 2011-02-03 WO disclosed
US-20110024677-A1 Processes for forming alkylated aryl phosphite compositions from complex hydrocarbon streams ADDIVANT USA, LLC 2011-02-03 US disclosed
US-20110028619-A1 Hydrolytically stable phosphite compositions SI GROUP, INC. 2011-02-03 US disclosed
US-20100197837-A1 POLYMERS WITH LOW GEL CONTENT AND ENHANCED GAS-FADING CHEMTURA CORPORATION (US) 2010-08-05 US disclosed
US-20100069542-A1 LIQUID AMYLARYL PHOSPHITE COMPOSITIONS AND ALKYLATE COMPOSITIONS FOR MANUFACTURING SAME CHEMTURA CORPORATION (US) 2010-03-18 US disclosed