Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.56 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.56 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.56 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600536 | 0.90 | ACHE (0.60) | ACHESIGMAR1APAF1 | |
| SCHEMBL11604676 | 0.89 | SIGMAR1 (0.51) | ACHEGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL11602637 | 0.88 | APAF1 (0.60) | ACHEGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL11603834 | 0.84 | SIGMAR1 (0.53) | ACHEGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL11604882 | 0.83 | ACHE (0.56) | ACHEGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL11602746 | 0.81 | ACHE (0.54) | ACHEGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL11603842 | 0.81 | APAF1 (0.52) | ACHEGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL11601045 | 0.81 | APAF1 (0.52) | ACHEGRIN1GRIN2AGRIN2DGRIN3B | |
| SCHEMBL11605701 | 0.81 | SIGMAR1 (0.57) | ACHESIGMAR1 | |
| SCHEMBL11605822 | 0.78 | SIGMAR1 (0.61) | ACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4085216-A | NEUROLEPTIC AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1978-04-18 | — | — | US | disclosed |