Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11604138 | 0.82 | ERN1 (0.55) | ERN1MAPTMEN1KMT2ACA12 | |
| SCHEMBL29653686 | 0.81 | MPL (0.51) | ERN1CYP2D6HPGDLMNACYP1A2 | |
| SCHEMBL9011319 | 0.81 | MPL (0.51) | ERN1CYP2D6HPGDLMNACYP1A2 | |
| SCHEMBL10508205 | 0.79 | NT5E (0.54) | MAPTKMT2AKDM4EALDH1A1CYP2D6 | |
| SCHEMBL28401054 | 0.78 | ERN1 (0.51) | ERN1MAPTMEN1KMT2ACA12 | |
| SCHEMBL4084347 | 0.78 | CASP6 (0.57) | MEN1KMT2AKDM4EALDH1A1CYP2D6 | |
| SCHEMBL4940575 | 0.75 | ERN1 (0.48) | ERN1MAPTMEN1KMT2ACA12 | |
| SCHEMBL14184043 | 0.75 | HSD17B10 (0.40) | MAPTCA12CA9KDM4EALDH1A1 | |
| SCHEMBL1730362 | 0.75 | ERN1 (0.52) | ERN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL20885914 | 0.75 | ERN1 (0.52) | ERN1MAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4120960-A | DIURETICS, SALURESIS | THE BOOTS COMPANY LIMITED (GB) | 1978-10-17 | — | — | US | disclosed |