SCHEMBL4084347

SCHEMBL4084347

Nc1ccc2c(S(=O)(=O)O)c(O)ccc2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 3/20 0.57
NT5E P21589 2/20 0.57
NSD2 O96028 1/20 0.57
DUSP3 P51452 1/20 0.57
PTPN5 P54829 1/20 0.57
PTPN11 Q06124 1/20 0.57
PLAU P00749 1/20 0.49
ENPP2 Q13822 1/20 0.42
ALDH1A1 P00352 5/20 0.41
HSD17B10 Q99714 4/20 0.41
CTDSP1 Q9GZU7 2/20 0.41
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
CA2 P00918 2/20 0.40
CYP2D6 P10635 1/20 0.40
TSHR P16473 2/20 0.38
RAPGEF4 Q8WZA2 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10570001 0.88 NT5E (0.58) CASP6NT5ENSD2DUSP3PTPN5
SCHEMBL2114169 0.86 CASP6 (0.51) CASP6NT5ENSD2DUSP3PTPN5
SCHEMBL9354745 0.84 CASP6 (0.50) CASP6NT5ENSD2DUSP3PTPN5
SCHEMBL29653686 0.82 MPL (0.51) NT5EHSD17B10CYP2C9CA2CYP2D6
SCHEMBL9011319 0.82 MPL (0.51) NT5EHSD17B10CYP2C9CA2CYP2D6
SCHEMBL10508205 0.81 NT5E (0.54) CASP6NT5ENSD2DUSP3PTPN5
SCHEMBL18354668 0.79 CASP6 (0.56) CASP6NT5ENSD2DUSP3PTPN5
SCHEMBL11604142 0.78 ERN1 (0.57) NT5EALDH1A1CYP2C9CYP2C19CYP2D6
SCHEMBL10897056 0.78 NT5E (0.51) CASP6NT5ENSD2DUSP3PTPN5
SCHEMBL5028738 0.77 CASP6 (0.54) CASP6NT5ENSD2DUSP3PTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638611-B2 Polarizer, coating liquid, and manufacturing method for polarizer NITTO DENKO CORPORATION (JP) 2009-12-29 US disclosed
US-20090187012-A1 POLARIZER, COATING LIQUID, AND MANUFACTURING METHOD FOR POLARIZER NITTO DENKO CORPORATION (JP) 2009-07-23 US disclosed