SCHEMBL11604607

SCHEMBL11604607

Cc1ccc(S(=O)(=O)n2cc(C)nc2C)cc1

nearest known ligand 0.76

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.76
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
ALDH3A1 P30838 2/20 0.46
POLB P06746 2/20 0.46
HTT P42858 2/20 0.46
NOD1 Q9Y239 1/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MAPT P10636 2/20 0.45
RAPGEF4 Q8WZA2 1/20 0.45
PKM P14618 2/20 0.44
KDM4E B2RXH2 1/20 0.44
UBE2N P61088 1/20 0.44
MMP2 P08253 1/20 0.43
SLC9A1 P19634 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7317576 0.83 ALDH1A1 (0.54) ALDH1A1L3MBTL1ALDH3A1POLBHTT
SCHEMBL6596170 0.80 LMNA (0.57) ALDH1A1LMNAL3MBTL1ALDH3A1POLB
SCHEMBL5306872 0.80 ALDH1A1 (0.51) ALDH1A1L3MBTL1ALDH3A1POLBHTT
SCHEMBL5591250 0.79 ALDH1A1 (0.50) ALDH1A1L3MBTL1ALDH3A1POLBHTT
SCHEMBL5271083 0.79 ALDH1A1 (0.50) ALDH1A1L3MBTL1ALDH3A1POLBHTT
SCHEMBL12137517 0.79 NR1H2 (0.56) ALDH1A1LMNAL3MBTL1ALDH3A1POLB
SCHEMBL1613854 0.79 ALDH1A1 (0.52) ALDH1A1LMNAL3MBTL1ALDH3A1POLB
SCHEMBL6596172 0.79 LMNA (0.56) ALDH1A1LMNAL3MBTL1ALDH3A1POLB
SCHEMBL28289511 0.77 ALDH1A1 (0.67) ALDH1A1LMNAL3MBTL1HTTMEN1
SCHEMBL5591804 0.75 ALDH1A1 (0.46) ALDH1A1LMNAL3MBTL1ALDH3A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4115060-A LOW TEMPERATURE BLEACHING, DETERGENTS FMC CORPORATION (US) 1978-09-19 US disclosed