Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591250 | 0.80 | ALDH1A1 (0.50) | ALDH1A1RAPGEF4L3MBTL1ALDH3A1POLB | |
| SCHEMBL5591442 | 0.76 | KMT2A (0.48) | ALDH1A1L3MBTL1ALDH3A1POLBHTT | |
| SCHEMBL11604607 | 0.75 | ALDH1A1 (0.76) | ALDH1A1RAPGEF4L3MBTL1ALDH3A1POLB | |
| SCHEMBL5591566 | 0.74 | TSHR (0.53) | ALDH1A1RAPGEF4L3MBTL1ALDH3A1POLB | |
| SCHEMBL8118164 | 0.73 | RAPGEF4 (0.43) | ALDH1A1RAPGEF4L3MBTL1ALDH3A1POLB | |
| SCHEMBL7317576 | 0.72 | ALDH1A1 (0.54) | ALDH1A1RAPGEF4L3MBTL1ALDH3A1POLB | |
| SCHEMBL5591491 | 0.71 | GRM4 (0.43) | ALDH1A1RAPGEF4POLBHTTCA1 | |
| SCHEMBL8508592 | 0.71 | ALDH1A1 (0.41) | ALDH1A1RAPGEF4L3MBTL1ALDH3A1POLB | |
| SCHEMBL5306872 | 0.70 | ALDH1A1 (0.51) | ALDH1A1RAPGEF4L3MBTL1ALDH3A1POLB | |
| SCHEMBL5271083 | 0.69 | ALDH1A1 (0.50) | ALDH1A1RAPGEF4L3MBTL1ALDH3A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007034277-A1 | ARYL SUBSTITUTED IMIDAZO [4,5-C] PYRIDINE COMPOUNDS AS C3A RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-03-29 | — | — | WO | disclosed |