Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603123 | 0.84 | KDM4E (0.35) | ALOX15KMT2AKDM4EGAAHPGD | |
| Potassium Ion SCHEMBL11602569 | 0.84 | ALOX15 (0.40) | ALOX15ACHEKMT2AKDM4EGAA | |
| SCHEMBL11532843 | 0.81 | KDM4E (0.47) | ACHEKMT2AKDM4EGAAHPGD | |
| SCHEMBL14332793 | 0.78 | KDM4E (0.53) | KMT2AKDM4EGAAHPGDGLA | |
| SCHEMBL11604724 | 0.77 | XDH (0.42) | KMT2AKDM4EHPGDHSD17B10MAPT | |
| SCHEMBL11605400 | 0.77 | XDH (0.43) | ACHEKMT2AKDM4EGAAHPGD | |
| SCHEMBL11607350 | 0.76 | CNR2 (0.47) | HPGDALDH1A1 | |
| SCHEMBL11591989 | 0.75 | ALDH1A1 (0.47) | KMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL11607517 | 0.73 | ALOX15 (0.43) | ALOX15KMT2AKDM4EGAAGLA | |
| SCHEMBL10292583 | 0.72 | KDM4E (0.42) | ALOX15KDM4EGAAHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083850-A | HYPOTENSIVE AGENTS | MEIJI SEIKA KAISHA LTD. (JA) | 1978-04-11 | — | — | US | disclosed |