Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11603448 | 0.98 | GABRA1 (0.41) | GABRA1GABRB2CLCN2FOLH1TSHR | |
| Hydrochloric Acid SCHEMBL11309435 | 0.98 | GABRA1 (0.41) | GABRA1GABRB2CLCN2FOLH1TSHR | |
| SCHEMBL4268183 | 0.82 | GABRA1 (0.46) | GABRA1GABRB2CLCN2FOLH1TSHR | |
| SCHEMBL6575704 | 0.80 | GABRA1 (0.44) | GABRA1GABRB2CLCN2FOLH1TSHR | |
| SCHEMBL14907983 | 0.80 | HPGD (0.43) | FOLH1TSHRHTTTP53GAA | |
| SCHEMBL21319068 | 0.80 | GABRA1 (0.44) | GABRA1GABRB2CLCN2FOLH1TSHR | |
| SCHEMBL166286 | 0.78 | GABRA1 (0.43) | GABRA1GABRB2CLCN2FOLH1TSHR | |
| SCHEMBL10805483 | 0.78 | GABRA1 (0.43) | GABRA1GABRB2CLCN2TSHRF2R | |
| SCHEMBL14907986 | 0.78 | PNMT (0.41) | FOLH1HTTCYP3A4CYP2C19 | |
| SCHEMBL19289171 | 0.78 | GABRA1 (0.43) | GABRA1GABRB2CLCN2FOLH1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097525-A | Aromatic amidines as antiviral agents in animals | PFIZER INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4066696-A | AROMATIC AMIDINES AS ANTIVIRAL AGENTS IN ANIMALS | PFIZER INC. (US) | 1978-01-03 | — | — | US | disclosed |
| US-4025555-A | Aromatic amidines as antiviral agents in animals | PFIZER INC. (US) | 1977-05-24 | — | — | US | disclosed |