SCHEMBL166286

SCHEMBL166286

CCc1ccccc1C(=S)S

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.43
GABRB2 P47870 3/20 0.43
GAA P10253 2/20 0.42
ALDH1A1 P00352 2/20 0.42
MAPT P10636 1/20 0.42
CLCN2 P51788 1/20 0.40
KMT2A Q03164 2/20 0.39
FOLH1 Q04609 1/20 0.38
TSHR P16473 1/20 0.38
F2R P25116 1/20 0.37
HTT P42858 2/20 0.36
TP53 P04637 1/20 0.35
MGLL Q99685 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28293863 0.83 FOLH1 (0.40) ALDH1A1KMT2AFOLH1HTTTP53
SCHEMBL4268183 0.82 GABRA1 (0.46) GABRA1GABRB2GAAALDH1A1MAPT
SCHEMBL7085183 0.80 LIPG (0.44) ALDH1A1FOLH1TSHRHTTTP53
SCHEMBL6575706 0.80 GABRA1 (0.44) GABRA1GABRB2GAAALDH1A1MAPT
SCHEMBL10919094 0.80 HPGD (0.43) GAAALDH1A1MAPTKMT2AFOLH1
SCHEMBL6575704 0.80 GABRA1 (0.44) GABRA1GABRB2ALDH1A1CLCN2FOLH1
SCHEMBL6894755 0.78 GAA (0.46) GABRA1GABRB2GAAALDH1A1MAPT
SCHEMBL11443422 0.78 GABRA1 (0.43) GABRA1GABRB2GAAALDH1A1MAPT
SCHEMBL11605474 0.78 GABRA1 (0.43) GABRA1GABRB2GAAALDH1A1MAPT
SCHEMBL19289171 0.78 GABRA1 (0.43) GABRA1GABRB2GAAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2611843-A1 METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS Lanxess Deutschland GmbH (DE) 2013-07-10 EP claimed
WO-2012028501-A1 METHOD FOR PRODUCING NITRILE RUBBERS IN ORGANIC SOLVENTS LANXESS DEUTSCHLAND GMBH (DE) 2012-03-08 WO claimed
US-9457234-B2 Golf ball DUNLOP SPORTS CO. LTD. (JP) 2016-10-04 US disclosed
US-9302158-B2 Golf ball DUNLOP SPORTS CO., LTD. (JP) 2016-04-05 US disclosed
US-20140357406-A1 GOLF BALL DUNLOP SPORTS CO., LTD. (JP) 2014-12-04 US disclosed
US-20140100058-A1 GOLF BALL Dunlop Sprorts Co., Ltd. (JP) 2014-04-10 US disclosed
EP-0365525-A4 LYMPHOCYTE INHIBITION BY HLA PEPTIDES 1990-12-12 EP disclosed
EP-0365525-A1 LYMPHOCYTE INHIBITION BY HLA PEPTIDES. UNIV LELAND STANFORD JUNIOR (US) 1990-05-02 EP disclosed
WO-1988005784-A1 LYMPHOCYTE INHIBITION BY HLA PEPTIDES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO (US) 1988-08-11 WO disclosed