Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606613 | 0.84 | DAO (0.53) | MEN1KMT2ADAOMMP2 | |
| SCHEMBL11607985 | 0.83 | MMP2 (0.57) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL29176354 | 0.78 | NPC1 (0.58) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL29176335 | 0.78 | NPC1 (0.74) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL11609706 | 0.77 | MMP2 (0.73) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL31265765 | 0.77 | NPC1 (0.64) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL11611110 | 0.77 | NPC1 (0.48) | MEN1KMT2ANPC1RAB9ADAO | |
| SCHEMBL22191811 | 0.76 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL11605284 | 0.75 | MMP2 (0.56) | MEN1KMT2AP2RX1DAOALDH1A1 | |
| SCHEMBL31265783 | 0.74 | KMT2A (0.57) | MEN1KMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046775-A | 4,5-Dihalopyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1977-09-06 | — | — | US | claimed |
| US-4084051-A | BACTERICIDES, HERBICIDES | STERLING DRUG INC. (US) | 1978-04-11 | — | — | US | disclosed |
| US-4046775-A | 4,5-Dihalopyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1977-09-06 | — | — | US | disclosed |
| US-3963480-A | Herbicidal pyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1976-06-15 | — | — | US | disclosed |