Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609706 | 0.87 | MMP2 (0.73) | MMP2KMT2ANPC1RAB9ADAO | |
| SCHEMBL11606613 | 0.85 | DAO (0.53) | MMP2KMT2ADAOMEN1POLB | |
| SCHEMBL11606092 | 0.83 | CA1 (0.60) | MMP2KMT2AMEN1MAPTPOLB | |
| SCHEMBL11607016 | 0.83 | MEN1 (0.62) | MMP2KMT2ANPC1RAB9ADAO | |
| SCHEMBL11611110 | 0.81 | NPC1 (0.48) | MMP2KMT2ANPC1RAB9ADAO | |
| SCHEMBL11605284 | 0.79 | MMP2 (0.56) | MMP2KMT2ADAOMEN1ALDH1A1 | |
| SCHEMBL30762244 | 0.76 | NPC1 (0.57) | MMP2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL17422865 | 0.76 | NPC1 (0.57) | MMP2KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11611755 | 0.75 | P2RX1 (0.54) | DAOMAPT | |
| SCHEMBL17433428 | 0.75 | NPC1 (0.78) | NPC1RAB9ATP53ALDH1A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046775-A | 4,5-Dihalopyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1977-09-06 | — | — | US | claimed |
| US-3963480-A | Herbicidal pyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1976-06-15 | — | — | US | claimed |
| US-4084051-A | BACTERICIDES, HERBICIDES | STERLING DRUG INC. (US) | 1978-04-11 | — | — | US | disclosed |
| US-4046775-A | 4,5-Dihalopyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1977-09-06 | — | — | US | disclosed |
| US-3963480-A | Herbicidal pyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1976-06-15 | — | — | US | disclosed |