Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11607985 | 0.81 | MMP2 (0.57) | NPC1RAB9AMAP2K1MMP2MEN1 | |
| SCHEMBL11607016 | 0.77 | MEN1 (0.62) | NPC1RAB9AMMP2MEN1KMT2A | |
| SCHEMBL11606613 | 0.76 | DAO (0.53) | MAP2K1MMP2MEN1POLBKMT2A | |
| SCHEMBL7861893 | 0.76 | MAPT (0.69) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4158650 | 0.73 | HDAC1 (0.58) | NPC1RAB9AHPGDNFKB1NFKB2 | |
| SCHEMBL11609706 | 0.72 | MMP2 (0.73) | NPC1RAB9ASMN1; SMN2MMP2MEN1 | |
| SCHEMBL11607921 | 0.71 | MAP2K1 (0.62) | MAP2K1MMP2DAO | |
| SCHEMBL9835752 | 0.71 | NPC1 (0.53) | NPC1RAB9AHPGDNFKB1NFKB2 | |
| SCHEMBL31236186 | 0.71 | ALDH1A1 (0.62) | NPC1RAB9AHPGDNFKB1NFKB2 | |
| SCHEMBL31236185 | 0.71 | ALDH1A1 (0.62) | NPC1RAB9AHPGDNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4084051-A | BACTERICIDES, HERBICIDES | STERLING DRUG INC. (US) | 1978-04-11 | — | — | US | disclosed |
| US-4046775-A | 4,5-Dihalopyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1977-09-06 | — | — | US | disclosed |
| US-3963480-A | Herbicidal pyrrole-2-carboxamides | STERLING DRUG INC. (US) | 1976-06-15 | — | — | US | disclosed |