SCHEMBL11607474

SCHEMBL11607474

COC(=O)c1cccnc1NS(=O)(=O)NC(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
CNR2 P34972 1/20 0.46
RAB9A P51151 3/20 0.44
HPGD P15428 1/20 0.44
POLB P06746 3/20 0.44
KDM4E B2RXH2 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
SLC40A1 Q9NP59 1/20 0.44
MAP2K1 Q02750 1/20 0.42
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
PKM P14618 1/20 0.40
BDKRB1 P46663 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
HTT P42858 2/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11604345 0.85 CNR2 (0.49) ALDH1A1CNR2RAB9AHPGDPOLB
SCHEMBL11612426 0.83 CNR2 (0.44) ALDH1A1CNR2RAB9AHPGDPOLB
SCHEMBL14575165 0.81 CNR2 (0.51) ALDH1A1CNR2RAB9AHPGDPOLB
SCHEMBL11612201 0.81 SLC40A1 (0.46) ALDH1A1CNR2RAB9AHPGDPOLB
SCHEMBL11607709 0.79 KDM4E (0.48) ALDH1A1CNR2RAB9AHPGDPOLB
SCHEMBL10355498 0.77 TSHR (0.56) ALDH1A1HPGDPOLBKDM4ETDP1
SCHEMBL29726034 0.77 TSHR (0.56) ALDH1A1HPGDPOLBKDM4ETDP1
SCHEMBL11604657 0.77 ALDH1A1 (0.46) ALDH1A1CNR2RAB9AHPGDPOLB
SCHEMBL23079017 0.76 OPRK1 (0.41) ALDH1A1RAB9AHPGDKDM4ELMNA
SCHEMBL29781382 0.76 SLC40A1 (0.38) ALDH1A1KDM4ESLC40A1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4014888-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-03-29 US claimed
US-4129734-A HERBICIDE THE DOW CHEMICAL COMPANY (US) 1978-12-12 US disclosed
US-4129733-A HERBICIDE THE DOW CHEMICAL COMPANY (US) 1978-12-12 US disclosed
US-4128551-A HERBICIDE THE DOW CHEMICAL CO. (US) 1978-12-05 US disclosed
US-4098792-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-07-04 US disclosed
US-4085279-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-18 US disclosed
US-4085278-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-18 US disclosed
US-4082758-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-04 US disclosed
US-4082759-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1978-04-04 US disclosed
US-4058533-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-11-15 US disclosed
US-4014888-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1977-03-29 US disclosed
US-3989507-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1976-11-02 US disclosed