Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11607629 | 1.00 | KCNE1 (0.40) | KCNE1KCNQ1MAOAMAOBLTB4R | |
| SCHEMBL11607634 | 1.00 | KCNE1 (0.40) | KCNE1KCNQ1MAOAMAOBLTB4R | |
| SCHEMBL10644246 | 0.77 | IDO1 (0.49) | KCNE1KCNQ1MAOAMAOBLTB4R | |
| SCHEMBL7253517 | 0.77 | IDO1 (0.49) | KCNE1KCNQ1MAOAMAOBLTB4R | |
| SCHEMBL10644259 | 0.77 | IDO1 (0.49) | KCNE1KCNQ1MAOAMAOBLTB4R | |
| SCHEMBL9765413 | 0.75 | KCNE1 (0.47) | KCNE1KCNQ1KMT2AMEN1 | |
| SCHEMBL10514021 | 0.72 | KCNE1 (0.35) | KCNE1KCNQ1MAOAMAOBKMT2A | |
| SCHEMBL11931751 | 0.71 | KMT2A (0.38) | KCNE1KCNQ1MAOAMAOBKMT2A | |
| SCHEMBL18192115 | 0.70 | OPRD1 (0.36) | KCNE1KCNQ1MAOAMAOBLTB4R | |
| SCHEMBL18192116 | 0.70 | OPRD1 (0.36) | KCNE1KCNQ1MAOAMAOBLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110347-A | ANTIHYPERTENSIVE | BEECHAM GROUP LIMITED (GB) | 1978-08-29 | — | — | US | disclosed |
| US-4105668-A | 6-AMINO-2,2-DIMETHYL-3-(1 -SUBSTITUTED TETRAZOL-5-YL)PENAM COMPOUND REACTED WITH HYDROGEN FLUORIDE | PFIZER INC. (US) | 1978-08-08 | — | — | US | disclosed |