SCHEMBL11608

SCHEMBL11608

N#Cc1ccccc1B(O)O

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
ENPP2 Q13822 3/20 0.41
ESR2 Q92731 1/20 0.41
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38
GAA P10253 2/20 0.37
POLB P06746 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
PDK2 Q15119 1/20 0.36
NOTUM Q6P988 1/20 0.36
ORAI1 Q96D31 1/20 0.35
ORAI2 Q96SN7 1/20 0.35
ORAI3 Q9BRQ5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29468918 1.00 TSHR (0.50) TSHRENPP2ESR2ALDH1A1HTT
1,3-Propanediol SCHEMBL4733793 0.88 TSHR (0.41) TSHRENPP2ESR2ALDH1A1HTT
SCHEMBL16276509 0.86 TSHR (0.46) TSHRENPP2ESR2ALDH1A1HTT
SCHEMBL7375093 0.80 TSHR (0.40) TSHRENPP2ESR2ALDH1A1GAA
SCHEMBL21143321 0.80 TSHR (0.40) TSHRENPP2ESR2ALDH1A1GAA
SCHEMBL3326323 0.80 TSHR (0.45) TSHRENPP2ESR2ALDH1A1CA1
SCHEMBL29383413 0.80 TSHR (0.45) TSHRENPP2ESR2ALDH1A1CA1
SCHEMBL19785358 0.79 TSHR (0.39) TSHRENPP2L3MBTL1PDK2NOTUM
SCHEMBL561951 0.79 NOTUM (0.39) TSHRENPP2ESR2ALDH1A1CA1
SCHEMBL18340951 0.79 TSHR (0.39) TSHRENPP2ESR2ALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1968 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
CN-119674208-A PEO-PAN-based polymer electrolyte membrane and preparation method and application thereof 山东创鲁先进电池科技有限公司 2025-03-21 CN claimed
CN-115959993-B Synthesis method of 2-aryl propionic acid compound 山东中医药大学 2025-01-07 CN claimed
CN-118878402-A Preparation method of trifluoromethyl ketone compound based on palladium catalysis of C-N bond cleavage 大连理工大学 2024-11-01 CN claimed
CN-117352743-B Sodium ion battery positive electrode material, preparation method thereof, positive electrode plate, battery and electricity utilization device 宁德时代新能源科技股份有限公司 2024-04-12 CN claimed
CN-117865773-A Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling 大连理工大学 2024-04-12 CN claimed
CN-117352743-A Sodium ion battery positive electrode material, preparation method thereof, positive electrode plate, battery and electricity utilization device 宁德时代新能源科技股份有限公司 2024-01-05 CN claimed
EP-3704211-B1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO LTD (KR) 2023-12-27 EP claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
US-20080312451-A1 Process For the Preparation of Sartan Derivatives and Intermediates Useful in Such Process KRKA, D.D. NOVO MESTO (SK) 2008-12-18 US claimed
WO-2008129077-A2 CRYSTALLINE 1-(CYCLOHEXYLOXYCARBONYLOXY) ETHYL 1-((2'-CYANOBIPHENYL-4-YL)METHYL)-2-ETHOXY-1H-BENZO[D]IMIDAZOLE-7-CARBOXYLATE AND A PROCESS FOR ITS PREPARATION KRKA, D.D. NOVO MESTO (SI) 2008-10-30 WO claimed
US-7432278-B2 Dicationic imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines as antiprotozoal agents THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2008-10-07 US claimed
EP-1931655-A2 A PROCESS FOR THE PREPARATION OF SARTAN DERIVATIVES AND INTERMEDIATES USEFUL IN SUCH PROCESS KRKA, D.D., Novo Mesto (SI) 2008-06-18 EP claimed
WO-2008039827-A2 POLYMER SYSTEMS FOR LUNG VOLUME REDUCTION THERAPY AERIS THERAPEUTICS, INC. (US) 2008-04-03 WO claimed
WO-2007039117-A2 A PROCESS FOR THE PREPARATION OF SARTAN DERIVATIVES AND INTERMEDIATES USEFUL IN SUCH PROCESS KRKA, D.D., NOVO, MESTO (SI) 2007-04-12 WO claimed
EP-1764365-A1 A process for the preparation of sartan derivates and intermediates useful in such process KRKA, D.D., Novo Mesto (SI) 2007-03-21 EP claimed
EP-1745045-A2 NOVEL DICATIONIC IMIDAZO 1,2-a PYRIDINES AND 5,6,7,8-TE TRAHYDRO-IMIDAZO 1,2a PYRIDINES AS ANTIPROTOZOAL AGENTS The University of North Carolina at Chapel Hill (US) 2007-01-24 EP claimed
US-20050282853-A1 Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8,-tetrahydro-imidazo[1,2,-a]pyridines as antiprotozoal agents BOYKIN DAVID W 2005-12-22 US claimed
WO-2005086808-A2 NOVEL DICATIONIC IMIDAZO[1,2-a]PYRIDINES AND 5,6,7,8-TETRAHYDRO-IMIDAZO[1,2a]PYRIDINES AS ANTIPROTOZOAL AGENTS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2005-09-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050282853-A1 Novel dicationic imidazo[1,2-a]pyridines and 5,6,7,8,-tetrahydro-imidazo[1,2,-a]pyridines as antiprotozoal agents PBRM1, QDPR, DHPS TSHR 2689/4885ENPP2 3594/4885ESR2 4686/4885
US-20080312451-A1 Process For the Preparation of Sartan Derivatives and Intermediates Useful in Such Process MC5R, NPY5R, ADRA1D TSHR 70/4885ENPP2 2923/4885ESR2 1627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.