Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.33 |
| ▸ | CCR8 | P51685 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874577 | 0.84 | KDM4E (0.56) | KDM4EMEN1KMT2ASLC1A5NOS3 | |
| SCHEMBL11171844 | 0.80 | KDM4E (0.53) | KDM4ESLC1A5CD274ALDH1A1LMNA | |
| SCHEMBL11138427 | 0.78 | KDM4E (0.66) | KDM4EMEN1KMT2ASLC1A5NOS3 | |
| SCHEMBL6754019 | 0.78 | ALDH1A1 (0.41) | KDM4EMEN1KMT2AKEAP1ALDH1A1 | |
| SCHEMBL9359315 | 0.76 | KDM4E (0.63) | KDM4EMEN1KMT2ASLC1A5ALDH1A1 | |
| SCHEMBL3920113 | 0.75 | KDM4E (0.59) | KDM4EMEN1KMT2ASLC1A5NOS3 | |
| SCHEMBL11062933 | 0.72 | KDM4E (0.59) | KDM4EMEN1KMT2ASLC1A5CD274 | |
| SCHEMBL1705163 | 0.72 | KDM4E (0.46) | KDM4EMEN1KMT2ANOS3NOS1 | |
| SCHEMBL409030 | 0.71 | KDM4E (0.55) | KDM4EMEN1KMT2ANOS3NOS1 | |
| SCHEMBL11132719 | 0.71 | KDM4E (0.58) | KDM4EMEN1KMT2ASLC1A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076719-A | Substituted pyridinyl methoxy (or 1-methyl methoxy)benzeneamines | THE DOW CHEMICAL COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4063928-A | Composition and method of controlling undesired plant growth with substituted pyridinyloxy(thio)phenyl -acetamides, -ureas and urea derivatives | THE DOW CHEMICAL COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4030910-A | Substituted pyridinyloxy(thio)phenyl -acetamides, -ureas and urea derivatives, herbicidal compositions and methods containing same | THE DOW CHEMICAL COMPANY (US) | 1977-06-21 | — | — | US | disclosed |
| US-4028092-A | Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthiophenylurea herbicides | THE DOW CHEMICAL COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-4026937-A | Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthio-phenylureas | THE DOW CHEMICAL COMPANY (US) | 1977-05-31 | — | — | US | disclosed |
| US-4003906-A | Substituted pyridinyl methylthio or (methylsulfonyl)benzeneamines | THE DOW CHEMICAL COMPANY (US) | 1977-01-18 | — | — | US | disclosed |
| US-4003733-A | HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1977-01-18 | — | — | US | disclosed |
| US-4003734-A | Substituted pyridinyloxy(thio)phenyl-acetamides, -ureas and urea derivatives and herbicidal compositions and methods containing said compounds | THE DOW CHEMICAL COMPANY (US) | 1977-01-18 | — | — | US | disclosed |
| US-3991068-A | Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthiophenylureas | THE DOW CHEMICAL COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
| US-3987050-A | SUBSTITUTED PYRIDINYLALKOXY-, PYRIDINYLALKYLSULFONYL AND PYRIDINYLALKYLTHIO-PHENYL-LOWER-ALKANAMIDES | THE DOW CHEMICAL COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3962265-A | H'-(4-((6-CHLORO-2-PYRIDINYL)OXY)PHENYL)-N-METHYL-N-(1-METHYL-2-PROPYNYL)UREA | THE DOW CHEMICAL COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3931200-A | Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthio- phenylureas | THE DOW CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931201-A | HERBICIDE | THE DOW CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | disclosed |