Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605716 | 0.79 | LMNA (0.48) | ALDH1A1LMNAMAPK1TDP1SLC6A2 | |
| SCHEMBL11608233 | 0.78 | NPC1 (0.41) | ALDH1A1LMNAMAPK1SLC6A2SLC6A3 | |
| SCHEMBL11606363 | 0.74 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPK1TDP1SLC6A2 | |
| SCHEMBL11613178 | 0.71 | ESR1 (0.41) | ALDH1A1LMNATDP1SLC6A2POLB | |
| SCHEMBL11607189 | 0.71 | IDO1 (0.41) | ALDH1A1POLBALOX15KMT2AHTT | |
| SCHEMBL14972964 | 0.70 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPK1TDP1POLB | |
| SCHEMBL8923884 | 0.69 | TDP1 (0.62) | ALDH1A1LMNAMAPK1TDP1SLC6A2 | |
| SCHEMBL11609585 | 0.69 | ALDH1A1 (0.36) | ALDH1A1PKMTSHRRAB9A | |
| SCHEMBL11609503 | 0.69 | FDPS (0.33) | — | |
| SCHEMBL27939896 | 0.69 | TDP1 (0.58) | ALDH1A1LMNAMAPK1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083989-A | MORPHOGENETIC HORMONAL MIMETIC ACTIVITY | CHEVRON RESEARCH COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-3988471-A | Insect control employing certain benzoates | CHEVRON RESEARCH COMPANY (US) | 1976-10-26 | — | — | US | disclosed |