Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MAT2A | P31153 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11607181 | 0.84 | CASR (0.63) | CASRNR1I2EGFRADRA2AADORA3 | |
| SCHEMBL11634768 | 0.84 | MAPT (0.53) | DHODHLMNAMAPTMAT2APTGER1 | |
| SCHEMBL11460555 | 0.81 | MAPT (0.53) | DHODHLMNAMAPTPTGER1CYP1A2 | |
| SCHEMBL11610757 | 0.81 | NR1I2 (0.58) | DHODHLMNAMAPTCASRALDH1A1 | |
| SCHEMBL6872385 | 0.80 | MAPT (0.53) | FNTAFNTBLMNAMAPTMAT2A | |
| SCHEMBL11609021 | 0.80 | CASR (0.45) | FNTAFNTBMAPTCYP1A2CYP2C19 | |
| SCHEMBL11608488 | 0.78 | HPGD (0.53) | LMNACYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL5420530 | 0.78 | ALDH1A1 (0.59) | KIF11DHODHLMNAMAPTPTGER1 | |
| SCHEMBL11212672 | 0.77 | MAPT (0.50) | DHODHLMNAMAPTPTGER1CYP1A2 | |
| SCHEMBL11602843 | 0.77 | CASR (0.68) | LMNAMAPTPTGER1CASRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |
| US-4067868-A | Production of quinazolinone compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-01-10 | — | — | US | disclosed |