Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615830 | 0.87 | HDAC3 (0.44) | RAB9AGAASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL11615866 | 0.86 | PTGDR2 (0.45) | PTGDR2GAASMN1; SMN2ALDH1A1LMNA | |
| Oxirane SCHEMBL11614994 | 0.79 | ABCB11 (0.42) | PTGDR2RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11609351 | 0.79 | PTGDR2 (0.44) | PTGDR2RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11616942 | 0.79 | RAB9A (0.43) | PTGDR2RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11613326 | 0.79 | GAA (0.43) | PTGDR2RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11616970 | 0.79 | PTGDR2 (0.45) | PTGDR2RAB9AGAASMN1; SMN2LMNA | |
| SCHEMBL11619002 | 0.79 | GAA (0.47) | PTGDR2RAB9AGAAPOLBALOX15 | |
| SCHEMBL11614081 | 0.78 | RAB9A (0.43) | PTGDR2RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11508802 | 0.78 | GRM5 (0.34) | SMN1; SMN2ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |