Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL11611564

CCCCCCCCCCCCCCCCN(C(=O)O)C(S)CCCCCCC.N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.47
FFAR1 O14842 2/20 0.47
MAPT P10636 1/20 0.42
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
FFAR4 Q5NUL3 1/20 0.40
ACE2 Q9BYF1 1/20 0.40
EPHX2 P34913 1/20 0.38
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10784891 0.78 CA2 (0.41) GPR84FFAR1MAPTLCKPPARD
SCHEMBL1759008 0.76 EPHX2 (0.54) GPR84FFAR1PPARDFFAR4ACE2
SCHEMBL10529104 0.72 CA12 (0.42) GPR84FFAR1MAPTACE2EPHX2
SCHEMBL6251336 0.71 GPR84 (0.46) GPR84FFAR1MAPTLCKPPARD
SCHEMBL29201414 0.71 MAPT (0.44) GPR84FFAR1MAPTLCKPPARD
SCHEMBL11355835 0.70 EPHX2 (0.42) GPR84FFAR1PPARDFFAR4ACE2
SCHEMBL15225281 0.70 FAAH (0.40) GPR84FFAR1MAPTPPARDFFAR4
SCHEMBL15224882 0.70 FAAH (0.40) GPR84FFAR1MAPTPPARDFFAR4
SCHEMBL1416635 0.70 EPHX1 (0.43) GPR84FFAR1PPARDFFAR4ACE2
SCHEMBL1416748 0.70 EPHX1 (0.43) GPR84FFAR1PPARDFFAR4ACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4081386-A ANTIOXIDANTS THE LUBRIZOL CORPORATION (US) 1978-03-28 US disclosed