Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612313 | 0.92 | HPGD (0.48) | KMT2AMEN1PTGER4MAPTRAB9A | |
| SCHEMBL11617777 | 0.90 | PTGER4 (0.41) | KMT2AMEN1PTGER4PTGDR2MAPT | |
| SCHEMBL11616869 | 0.86 | POLB (0.48) | KMT2AMEN1PTGDR2MAPTRAB9A | |
| SCHEMBL11615339 | 0.76 | KMT2A (0.49) | KMT2AMEN1MAPTRAB9ACYP1A2 | |
| SCHEMBL11613391 | 0.74 | KMT2A (0.44) | KMT2AMEN1PTGER4PTGDR2MAPT | |
| SCHEMBL11616738 | 0.74 | MAPK1 (0.45) | KMT2AMEN1MAPTRAB9ANPSR1 | |
| SCHEMBL11614116 | 0.73 | PTGIR (0.44) | RAB9ANPC1KDM4EHPGD | |
| SCHEMBL11611124 | 0.72 | NPC1 (0.47) | KMT2AMEN1PTGDR2RAB9ANPC1 | |
| SCHEMBL11614849 | 0.69 | NPSR1 (0.49) | KMT2AMEN1MAPTRAB9ACYP2C9 | |
| SCHEMBL11613653 | 0.69 | MAPT (0.52) | KMT2AMEN1PTGER4PTGDR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |