Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612175 | 0.92 | KMT2A (0.45) | HPGDKMT2ARAB9AMAPTMEN1 | |
| SCHEMBL11617777 | 0.89 | PTGER4 (0.41) | TDP1KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL11616869 | 0.81 | POLB (0.48) | HPGDKMT2ARAB9AMAPTMEN1 | |
| SCHEMBL11616738 | 0.73 | MAPK1 (0.45) | HPGDKMT2ARAB9AMAPTMEN1 | |
| SCHEMBL11614163 | 0.71 | PTGDR2 (0.39) | HPGDTDP1MAPTPOLBRXFP1 | |
| SCHEMBL8676348 | 0.70 | L3MBTL1 (0.73) | TDP1L3MBTL1KMT2ARAB9AMAPT | |
| SCHEMBL11613391 | 0.70 | KMT2A (0.44) | HPGDKMT2ARAB9AMAPTMEN1 | |
| SCHEMBL11613653 | 0.69 | MAPT (0.52) | TDP1KMT2ARAB9AMAPTMEN1 | |
| SCHEMBL11615339 | 0.69 | KMT2A (0.49) | KMT2ARAB9AMAPTMEN1ALDH1A1 | |
| SCHEMBL11615729 | 0.68 | TP53 (0.45) | HPGDKMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |