Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11612175 | 0.90 | KMT2A (0.45) | PTGER4MAPTKMT2AMEN1PTGDR2 | |
| SCHEMBL11612313 | 0.89 | HPGD (0.48) | PTGER4MAPTKMT2AMEN1TDP1 | |
| SCHEMBL11616738 | 0.85 | MAPK1 (0.45) | MAPTKMT2AMEN1MAPK1KDM4E | |
| SCHEMBL11616869 | 0.81 | POLB (0.48) | MAPTKMT2AMEN1PTGDR2CYP1A2 | |
| SCHEMBL11613653 | 0.81 | MAPT (0.52) | PTGER4MAPTKMT2AMEN1TDP1 | |
| SCHEMBL11613221 | 0.76 | MAPT (0.44) | MAPTKMT2AMEN1PTGDR2CYP1A2 | |
| SCHEMBL11615774 | 0.73 | KMT2A (0.53) | MAPTKMT2AMEN1TDP1CYP1A2 | |
| SCHEMBL11613986 | 0.72 | KMT2A (0.53) | MAPTKMT2AMEN1TDP1CYP1A2 | |
| SCHEMBL11610558 | 0.72 | MAPT (0.50) | MAPTKMT2AMEN1TDP1KDM4E | |
| SCHEMBL11615397 | 0.71 | LMNA (0.45) | MAPTKMT2AMEN1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |