Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARA | Q07869 | 5/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.39 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617777 | 0.85 | PTGER4 (0.41) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11614116 | 0.79 | PTGIR (0.44) | KDM4EPPARGLMNAHPGDRAB9A | |
| SCHEMBL11612294 | 0.78 | RAB9A (0.48) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11611124 | 0.77 | NPC1 (0.47) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11611800 | 0.74 | PTGDR2 (0.45) | MAPK1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11612175 | 0.74 | KMT2A (0.45) | KDM4EALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL11612313 | 0.73 | HPGD (0.48) | ALDH1A1PPARGPPARAKMT2AMEN1 | |
| SCHEMBL11613221 | 0.73 | MAPT (0.44) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11616262 | 0.73 | PTGDR2 (0.47) | KDM4EALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11615729 | 0.72 | TP53 (0.45) | MAPK1ALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117145-A | DIURETIC, HYPOTENSIVE, ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4117143-A | USED AS ANTITHROMBOTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-26 | — | — | US | disclosed |
| US-4113957-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | disclosed |