SCHEMBL1161241

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1160829	0.89	RAF1 (0.38)	RAF1BRAFCYP11B1CYP11B2
	SCHEMBL11031834	0.85	MMP14 (0.37)	HTR2CRAF1BRAFFNTAFNTB
	SCHEMBL1161020	0.85	EGFR (0.42)	RAF1BRAFFNTAFNTBPGGT1B
	SCHEMBL1161162	0.85	BRAF (0.38)	RAF1BRAFEGFR
	SCHEMBL11028684	0.83	NOD1 (0.34)	RAF1BRAFFFAR1EGFR
	SCHEMBL1160800	0.79	BRAF (0.40)	RAF1BRAFEGFR
	SCHEMBL11029321	0.79	IDH1 (0.43)	RAF1BRAFEGFR
	SCHEMBL11027734	0.79	IDH1 (0.39)	RAF1BRAFEGFR
	SCHEMBL12873243	0.78	AURKA (0.42)	RAF1BRAFEGFR
	SCHEMBL11031849	0.78	IDH1 (0.40)	RAF1BRAFEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.