Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TACR2 | P21452 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136075 | 1.00 | IGF1R (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL5609032 | 0.98 | IGF1R (0.53) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL5609711 | 0.91 | CYP1A2 (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL10571160 | 0.88 | IGF1R (0.61) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL28184336 | 0.88 | IGF1R (0.61) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL6546754 | 0.85 | IGF1R (0.64) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL11395796 | 0.82 | IGF1R (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL9027693 | 0.82 | TAAR1 (0.48) | TAAR1ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL6270006 | 0.82 | ALDH1A1 (0.63) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL1805218 | 0.80 | CYP1A2 (0.56) | IGF1RALOX15CYP1A2CYP2A6TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4081386-A | ANTIOXIDANTS | THE LUBRIZOL CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
| US-4032461-A | PHOSPHORUS AND SULFUR CONTAINING AMIDES AND THIOAMIDES AS LUBRICATING OIL ADDITIVES AND LUBRICATING OIL COMPOSITIONS CONTAINING SAME | THE LUBRIZOL CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
| US-3962105-A | LUBRICATING COMPOSITIONS | THE LUBRIZOL CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |