Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136075 | 0.98 | IGF1R (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL11612548 | 0.98 | IGF1R (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL5609711 | 0.93 | CYP1A2 (0.52) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL6546754 | 0.87 | IGF1R (0.64) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL28184336 | 0.85 | IGF1R (0.61) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL10571160 | 0.85 | IGF1R (0.61) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL1805218 | 0.82 | CYP1A2 (0.56) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL6546878 | 0.82 | CYP1A2 (0.62) | IGF1RALOX15CYP1A2CYP2A6TAAR1 | |
| SCHEMBL18243517 | 0.81 | ALDH1A1 (0.55) | ALDH1A1CYP3A4 | |
| SCHEMBL18378057 | 0.81 | ALDH1A1 (0.48) | ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2019-10-22 | — | — | US | disclosed |
| CN-109478389-A | MULTI-LAYER DISPLAY WITH COLOR AND CONTRAST ENHANCEMENT | 三星电子株式会社 | 2019-03-15 | — | — | CN | disclosed |
| CN-109477972-A | The multilayer high grade of transparency display generated for light field | 三星电子株式会社 | 2019-03-15 | — | — | CN | disclosed |
| CN-109479125-A | The optical projection system of color and contrast with enhancing | 三星电子株式会社 | 2019-03-15 | — | — | CN | disclosed |
| CN-108026230-A | Antifouling composition | 巴斯夫欧洲公司 | 2018-05-11 | — | — | CN | disclosed |
| CN-107922571-A | Antifouling composition | 巴斯夫欧洲公司 | 2018-04-17 | — | — | CN | disclosed |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| US-7199139-B2 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2007-04-03 | — | — | US | disclosed |
| EP-1695716-A2 | Medicinal compositions containing diuretics and insulin sensitizers | Sankyo Company, Limited (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-20050288339-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2005-12-29 | — | — | US | disclosed |
| US-20040053974-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-0916651-B1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | SANKYO CO (JP) | 2003-10-15 | — | — | EP | disclosed |
| US-6103907-A | ALDOSE REDUCTASE INHIBITING ANTIDIABETIC AGENT | SANKYO COMPANY, LIMITED (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-0916651-A1 | PHENYLALKYLCARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1995025514-A1 | COMPOUNDS USEFUL AS ANXIOLYTIC, SEDATIVE, AND HYPNOTIC AGENTS | DISCOVERY THERAPEUTICS, INC. (US) | 1995-09-28 | — | — | WO | disclosed |
| US-4237132-A | ARTERIOSCLEROSIS, ANTICHOLESTEROL, ANTILIPEMIC | NIPPON SHINYAKU CO., LTD. (JP) | 1980-12-02 | — | — | US | disclosed |
| US-4162331-A | USED IN THE TREATMENT OR PREVENTION OF ARTERIOSCLEROSIS | NIPPON SHINYAKU CO., LTD. (JP) | 1979-07-24 | — | — | US | disclosed |
| US-4094991-A | ARTERIOSCLEROSIS, REDUCTION OF CHOLESTEROL AND TRIGLYCERIDES | NIPPON SHINYAKU CO., LTD. (JA) | 1978-06-13 | — | — | US | disclosed |
| US-4064252-A | ARTERIOSCLEROSIS | NIPPON SHINYAKU CO., LTD. (JA) | 1977-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053974-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | GPR119, INSR, IRS1 | IGF1R 9/4885ALOX15 1884/4885CYP1A2 4073/4885 |
| US-10451967-B2 | Acid- and radical-generating agent and method for generating acid and radical | CBR1, HAO2, CBR3 | IGF1R 698/4885ALOX15 192/4885CYP1A2 360/4885 |
| US-20160342084-A1 | ACID- AND RADICAL-GENERATING AGENT AND METHOD FOR GENERATING ACID AND RADICAL | CBR1, HAO2, CBR3 | IGF1R 698/4885ALOX15 192/4885CYP1A2 360/4885 |
| US-20050288339-A1 | Medicinal compositions containing diuretic and insulin resistance-improving agent | GPR119, INSR, IRS1 | IGF1R 9/4885ALOX15 1884/4885CYP1A2 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.