Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 9/20 | 0.50 |
| ▸ | MAOA | P21397 | 8/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11567039 | 0.81 | MAPT (0.54) | PTGS2NPC1MAPTRAB9AKDM4E | |
| SCHEMBL11732182 | 0.79 | PTGS2 (0.50) | PTGS2NPC1MAPTRAB9AKDM4E | |
| SCHEMBL11732178 | 0.79 | PTGS2 (0.50) | PTGS2NPC1MAPTRAB9AKDM4E | |
| SCHEMBL11612561 | 0.78 | MAOB (0.53) | PTGS2KMT2AALDH1A1MAOBMAOA | |
| SCHEMBL11567038 | 0.78 | PTGS2 (0.54) | PTGS2NPC1MAPTRAB9AKDM4E | |
| SCHEMBL11423923 | 0.75 | SLC16A3 (0.57) | NPC1MAPTRAB9AKDM4EKMT2A | |
| SCHEMBL11617172 | 0.74 | PTPN1 (0.50) | MAPTKMT2AMEN1ALDH1A1MAOB | |
| SCHEMBL11508405 | 0.74 | ALDH1A1 (0.60) | PTGS2NPC1MAPTRAB9AKDM4E | |
| SCHEMBL11724240 | 0.74 | PTGS2 (0.49) | PTGS2NPC1MAPTRAB9AKDM4E | |
| SCHEMBL11724227 | 0.74 | PTGS2 (0.49) | PTGS2NPC1MAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4066655-A | 4,10-Dihydro-4,10-dioxo-1H-1-benzopyrano[3,2-b]pyridine-3-carboxylic acids, salts and esters | WARNER-LAMBERT COMPANY (US) | 1978-01-03 | — | — | US | disclosed |