SCHEMBL116134

SCHEMBL116134

[SiH3]O[SiH2]Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
CALM1 P0DP23 1/20 0.39
IDO1 P14902 2/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
ALDH1A1 P00352 2/20 0.36
LOXL2 Q9Y4K0 2/20 0.36
TP53 P04637 1/20 0.36
TRPA1 O75762 1/20 0.36
AGXT P21549 1/20 0.36
MAOB P27338 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
ALOX12 P18054 1/20 0.35
CASP1 P29466 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
CYP2A6 P11509 1/20 0.33
HTR2A P28223 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL873698 0.98 TSHR (0.39) TSHRCALM1IDO1CES2CES1
SCHEMBL1072585 0.88 TP53 (0.33) TSHRCALM1IDO1CES2CES1
SCHEMBL9121524 0.84 TSHR (0.31) TSHRALDH1A1TRPA1
SCHEMBL10731613 0.82 TSHR (0.34) TSHRCALM1IDO1ALDH1A1LOXL2
SCHEMBL320639 0.79 TSHR (0.43) TSHRCALM1IDO1ALDH1A1LOXL2
SCHEMBL11494485 0.79 TSHR (0.32) TSHRCALM1IDO1
SCHEMBL11497720 0.79 TSHR (0.32) TSHRCALM1IDO1
SCHEMBL9229144 0.76 IDO1 (0.41) IDO1LOXL2AGXTMAOBTAAR1
SCHEMBL485741 0.76 ALDH1A1 (0.42) TSHRIDO1ALDH1A1LOXL2MAOB
SCHEMBL6001246 0.75 TP53 (0.30) TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6099 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12640364-B2 High capacity, long cycle life battery anode materials, compositions and methods DYNAMIC MATERIAL SYSTEMS LLC (US) 2026-05-26 US claimed
CN-116948399-B Novel doping agent for ion mobility spectrometry Shenyang Fire Research Institute Of Mem (CN) 2026-05-26 CN claimed
EP-4735528-A1 PPS-BASED COMPOSITION WITH ENHANCED TOUGHNESS AND FLAME RETARDANCY AND MOLDED ARTICLE USING THE SAME Syensqo Specialty Polymers USA, LLC (US) 2026-05-06 EP claimed
US-20260117139-A1 SILICONE OILS MATCHING REFRACTIVE INDEX OF TRANSPARENT MATERIAL/OPTICALLY CLEAR LIQUID WITH A KINEMATIC VISCOSITY IN A WELL-DEFINED RANGE PRECIFLEX SA (CH) 2026-04-30 US claimed
US-20260109879-A1 SILICONE COATING COMPOSITION WITH MICA DOW SILICONES CORP (US) 2026-04-23 US claimed
EP-4720408-A1 DEFOAMING AGENT AND COMPOSITIONS CONTAINING THE DEFOAMING AGENT Solenis Technologies Cayman, L.P. (CH) 2026-04-08 EP claimed
EP-4695334-A1 FLAME-RETARDANT PPS-BASED COMPOSITION AND MOLDED ARTICLE USING THE SAME Syensqo Specialty Polymers USA, LLC (US) 2026-02-18 EP claimed
US-12529410-B2 Zero-frequency absorber material Technology Innovation Institute—Sole Proprietorship LLC (AE) 2026-01-20 US claimed
EP-4655343-A1 SILICONE COATING COMPOSITION WITH MICA Dow Silicones Corporation (US) 2025-12-03 EP claimed
US-12486235-B2 Metal oxide nanoparticle with alkylsiloxane ligands bonded thereto CUBICPV INC. (US) 2025-12-02 US claimed
US-4356098-A Stable ferrofluid compositions and method of making same FERROFLUIDICS CORPORATION (US) 1982-10-26 US claimed
US-4250075-A CONTAINING PHENYL RADICALS, CURABLE DOW CORNING CORPORATION (US) 1981-02-10 US claimed
US-4238050-A CURED POLYSILOXANE DOW CORNING CORPORATION (US) 1980-12-09 US claimed
US-4114993-A COPOLYMER BLEND OF POLYSILOXANES, SILICA FILLER AMERICAN OPTICAL CORPORATION (US) 1978-09-19 US claimed
US-4065564-A REDUCED TACKINESS, ALUMINUM CHLOROHYDROXIDE COMPLEX LEVER BROTHERS COMPANY (US) 1977-12-27 US claimed
US-4053581-A ANTIPERSPIRANT SOLUTION CONTAINING A MIXTURE OF SUBSTANTIALLY VOLATILE AND SUBSTANTIALLY NON-VOLATILE SILOXANE LIQUIDS LEVER BROTHERS COMPANY (US) 1977-10-11 US claimed
US-3996187-A Optically clear filled silicone elastomers AMERICAN OPTICAL CORPORATION (US) 1976-12-07 US claimed
US-3996189-A CONTACT LENS AMERICAN OPTICAL CORPORATION (US) 1976-12-07 US claimed
US-3972850-A Hydrophobic windshield wipers and process for making same THE BOEING COMPANY (US) 1976-08-03 US claimed
US-3933678-A Optically clear organosilicon compounds DOW CORNING CORPORATION (US) 1976-01-20 US claimed