SCHEMBL485741

SCHEMBL485741

[SiH3]O[SiH2]CCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TAAR1 Q96RJ0 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
IDO1 P14902 2/20 0.39
MAOA P21397 4/20 0.38
MAOB P27338 3/20 0.38
TSHR P16473 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3682331 0.87 IDO1 (0.45) SMN1; SMN2HTR2AIDO1MAOAMAOB
SCHEMBL624547 0.85 MAOA (0.47) HTR2AIDO1MAOAMAOBSIGMAR1
SCHEMBL2495545 0.77 ALDH1A1 (0.42) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL116134 0.76 TSHR (0.40) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL873698 0.74 TSHR (0.39) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL17075381 0.74 TP53 (0.41) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL8381953 0.73 ALDH1A1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL251756 0.72 ALDH1A1 (0.38) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL29001290 0.72 SIGMAR1 (0.39) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL15135577 0.72 ALDH1A1 (0.38) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250064701-A1 COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN UNIVERSIDAD DE GRANADA (ES) 2025-02-27 US claimed
CN-114792589-A High-strength organosilicon silicon rubber disc-shaped suspension type porcelain and glass composite insulator 王福有 2022-07-26 CN claimed
US-20190055406-A1 TREATED INORGANIC PARTICULATE MATERIAL FOR IMPROVING PERFORMANCE OF CONSTRUCTION AND ASSEMBLY COMPOUNDS IMERYS USA, INC. 2019-02-21 US claimed
CN-105324551-A Treatment for non-caking mine rock dust IMERYS PIGMENTS INC 2016-02-10 CN claimed
EP-2943651-A1 TREATMENT FOR NON-CAKING MINE ROCK DUST Imerys Pigments, Inc. (US) 2015-11-18 EP claimed
EP-2926800-A1 COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN Universidad de Granada (ES) 2015-10-07 EP claimed
WO-2015054286-A1 TREATMENTS FOR NON-CAKING MINE ROCK DUST IMERYS PIGMENTS, INC. (US) 2015-04-16 WO claimed
WO-2014110202-A1 TREATMENT FOR NON-CAKING MINE ROCK DUST IMERYS PIGMENTS, INC. (US) 2014-07-17 WO claimed
EP-1819776-B1 AESTHETIC, STABLE CHROMATIC EMULSIONS AVON PROD INC (US) 2010-03-03 EP claimed
CN-1200675-C Hair styling composition UNILEVER PLC (NL) 2005-05-11 CN claimed
US-6689313-B2 ADJUSTING THE FRAGRANCE LEVEL IN A ROOM, ENCLOSURE OR OTHER ENVIRONMENT BY INCREMENTALLY ADDING A CLEAR NON-FOAMING EMULSIFIED, SOLUBILIZED OR INSOLUBLE FRAGRANCE TO A RECIRCULATING FOUNTAIN BATH & BODY WORKS, INC. 2004-02-10 US claimed
US-6623694-B1 Recirculating air freshening; polysiloxane, alcohol, emulsi-fier, fragrance oil and water BATH & BODY WORKS, INC. 2003-09-23 US claimed
US-20020110480-A1 Non-foaming water fountain method BATH & BODY WORKS, INC. 2002-08-15 US claimed
US-4476291-A Resins containing β-phenylethyl trifunctional siloxy units and method for making GENERAL ELECTRIC COMPANY (US) 1984-10-09 US claimed
EP-4103144-B1 COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS SYMRISE AG (DE) 2026-05-27 EP disclosed
WO-2026087745-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-30 WO disclosed
EP-4732825-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-29 EP disclosed
US-4070313-A PHENOLIC RESOLE, BLOWING AGENT, POLYSILOXANE UNION CARBIDE CORPORATION (US) 1978-01-24 US disclosed
US-4064154-A USEFUL IN HYDROGENATION, HYDROFORMYLATION, AND OLIGOMERIZATION REACTIONS DOW CORNING CORPORATION (US) 1977-12-20 US disclosed
US-3957715-A SILICONE RESIN HOWMET CORPORATION (US) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250064701-A1 COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN NDUFA10, NDUFB10, TIMM10 ALDH1A1 771/4885HPGD 258/4885ALOX15 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.