Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116134 | 0.98 | TSHR (0.40) | TSHRCALM1IDO1CES2CES1 | |
| SCHEMBL1072585 | 0.86 | TP53 (0.33) | TSHRCALM1IDO1CES2CES1 | |
| SCHEMBL9121524 | 0.82 | TSHR (0.31) | TSHRALDH1A1TRPA1 | |
| SCHEMBL10731613 | 0.80 | TSHR (0.34) | TSHRCALM1IDO1ALDH1A1LOXL2 | |
| SCHEMBL320639 | 0.77 | TSHR (0.43) | TSHRCALM1IDO1ALDH1A1LOXL2 | |
| SCHEMBL11494485 | 0.77 | TSHR (0.32) | TSHRCALM1IDO1 | |
| SCHEMBL11497720 | 0.77 | TSHR (0.32) | TSHRCALM1IDO1 | |
| SCHEMBL9229144 | 0.74 | IDO1 (0.41) | IDO1LOXL2AGXTMAOBTAAR1 | |
| SCHEMBL485741 | 0.74 | ALDH1A1 (0.42) | TSHRIDO1ALDH1A1LOXL2MAOB | |
| SCHEMBL6001246 | 0.73 | TP53 (0.30) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632426-A1 | COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE AND A CATIONIC POLYMER | L'Oréal (FR) | 2013-09-04 | — | — | EP | disclosed |
| EP-2632424-A1 | COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE AND A CATIONIC OR NONIONIC SURFACTANT. | L'Oréal (FR) | 2013-09-04 | — | — | EP | disclosed |
| EP-2632425-A1 | COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE, AN ANIONIC SURFACTANT AND A NONIONIC, AMPHOTERIC OR ZWITTERIONIC SURFACTANT | L'Oréal (FR) | 2013-09-04 | — | — | EP | disclosed |
| EP-2618801-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE HYGROSCOPIC SALT, AT LEAST ONE AROMATIC POLYOL ETHER AND AT LEAST ONE DIOL, AND COSMETIC TREATMENT PROCESS | L'Oréal (FR) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012110608-A2 | PROCESS FOR TREATING KERATIN FIBRES USING A SILICONE ELASTOMER IN COMBINATION WITH HEAT | L'OREAL (FR) | 2012-08-23 | — | — | WO | disclosed |
| WO-2012055811-A1 | COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE AND A CATIONIC OR NONIONIC SURFACTANT. | L'OREAL (FR) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012055805-A1 | COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE AND A SILICEOUS COSMETIC AGENT. | L'OREAL (FR) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012055809-A1 | COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE, AN ANIONIC SURFACTANT AND A NONIONIC, AMPHOTERIC OR ZWITTERIONIC SURFACTANT | L'OREAL (FR) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012055807-A1 | COSMETIC COMPOSITION COMPRISING A FATTY-CHAIN ALKOXYSILANE AND A CATIONIC POLYMER | L'OREAL (FR) | 2012-05-03 | — | — | WO | disclosed |
| WO-2012038536-A2 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE HYGROSCOPIC SALT, AT LEAST ONE AROMATIC POLYOL ETHER AND AT LEAST ONE DIOL, AND COSMETIC TREATMENT PROCESS | L'OREAL (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038538-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE QUATERNARY AMMONIUM ESTER AND AT LEAST ONE SOLUBLE SALT OF DIVALENT METALS, AND PROCESS USING THE SAID COMPOSITION | L'OREAL (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038534-A1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE CALCIUM SALT, AT LEAST ONE FATTY ALCOHOL, AT LEAST ONE CATIONIC SURFACTANT AND AT LEAST ONE THICKENER | L'OREAL (FR) | 2012-03-29 | — | — | WO | disclosed |
| US-20080274070-A1 | Method for permanently reshaping keratin fibers comprising applying a poorly concentrated reducing compositions followed by drying | L'OREAL S.A. (FR) | 2008-11-06 | — | — | US | disclosed |
| US-20080206177-A1 | Cosmetic composition comprising at least one cationic polyurethane and at least one polyethylene glycol ester, to be applied during hair dressing | L'OREAL, S.A. (FR) | 2008-08-28 | — | — | US | disclosed |
| US-20080206164-A1 | Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith | L'OREAL S.A. (FR) | 2008-08-28 | — | — | US | disclosed |
| US-20080185014-A1 | Method for permanently reshaping keratin fibers comprising applying a poorly concentrated reducing composition and intermediate drying | L'OREAL S.A. (FR) | 2008-08-07 | — | — | US | disclosed |
| US-7223720-B2 | Dialkyl(ene) alkoxy ether wax, a dialkyl(ene) carbonate, amphoteric and/or zwitterionic surfactant; and a cationic polymer for cleaning keratinous fibres; reduces the combing work on hair | COGNIS IP MANAGEMENT GMBH (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060177399-A1 | Pressurized device for hair fiber styling and use of the same for hair fiber styling and/or hair | L'OREAL S.A. (FR) | 2006-08-10 | — | — | US | disclosed |
| US-20050202985-A1 | Dialkyl(ene) alkoxy ether wax, a dialkyl(ene) carbonate, amphoteric and/or zwitterionic surfactant; and a cationic polymer for cleaning keratinous fibres; reduces the combing work on hair | COGNIS IP MANAGEMENT GMBH (DE) | 2005-09-15 | — | — | US | disclosed |
| US-5496544-A | CONTAINING MIXTURE OF SILICONE OIL/WAX/RESIN AND OPTIONALLY SILICONE GUM AND PHENYL SIMETHICONE; FACE MAKE-UP, EYE SHADOW, MAKE-UP AND BODY POWDERS | L'OREAL (FR) | 1996-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080206164-A1 | Cosmetic composition comprising at least one cationic polyurethane and at least one vinyl pyrrolidone homo- or copolymer, and method of styling therewith | PUF60, SRSF2, PCBP1 | TSHR 3039/4885CALM1 3090/4885IDO1 143/4885 |
| US-20080206177-A1 | Cosmetic composition comprising at least one cationic polyurethane and at least one polyethylene glycol ester, to be applied during hair dressing | CUTA, PHOSPHO1, DSG1 | TSHR 4574/4885CALM1 4447/4885IDO1 451/4885 |
| US-20060177399-A1 | Pressurized device for hair fiber styling and use of the same for hair fiber styling and/or hair | POLR1C, NACA, SHH | TSHR 983/4885CALM1 2345/4885IDO1 1913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.