SCHEMBL1161353

SCHEMBL1161353

CC(C)O[SiH2]CCCNC(N)=O

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TACR3 P29371 1/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3476354 0.82 EPHX1 (0.47) ALDH1A1TSHRL3MBTL1KMT2A
SCHEMBL3142448 0.80 TSHR (0.31) TSHR
SCHEMBL1897574 0.79 EPHX1 (0.34) ALDH1A1TSHRKMT2A
SCHEMBL20742801 0.78 TSHR (0.33) ALDH1A1TSHR
SCHEMBL28447315 0.77 BCAT2 (0.32)
SCHEMBL9194723 0.77 MEN1 (0.54) ALDH1A1KMT2A
SCHEMBL1770488 0.76 CA12 (0.34) TSHRKMT2A
SCHEMBL19209504 0.76 MEN1 (0.33) KMT2A
SCHEMBL8513100 0.76 EPHX1 (0.31)
SCHEMBL3150621 0.76 TSHR (0.34) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10702467-B2 Emulsion containing organosilicon-based portions of hollow spheres L'ORÉAL (FR) 2020-07-07 US disclosed
US-20170304183-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'ORÉAL (FR) 2017-10-26 US disclosed
US-9622946-B2 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2017-04-18 US disclosed
US-20130224267-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'OREAL (FR) 2013-08-29 US disclosed
EP-1579841-B1 Cosmetic composition comprising concave particles OREAL (FR) 2012-11-14 EP disclosed
EP-2462199-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'Oréal (FR) 2012-06-13 EP disclosed
US-20110217346-A1 EMULSION CONTAINING ORGANOSILICON-BASED PORTIONS OF HOLLOW SPHERES L'OREAL (FR) 2011-09-08 US disclosed
EP-2359908-A2 Cosmetic composition for lightening or unifying the complexion L'Oréal (FR) 2011-08-24 EP disclosed
WO-2011016144-A1 COMPOSITE PIGMENT AND METHOD FOR PREPARATION THEREOF L'OREAL (FR) 2011-02-10 WO disclosed
EP-1530961-B1 Emulsion containing hollow organosilicon particles OREAL (FR) 2009-08-05 EP disclosed
US-20070224141-A1 Kit containing two compositions L'OREAL (FR) 2007-09-27 US disclosed
EP-1800714-A1 Cosmetic composition comprising concave particles and a dispersant, manufacture and use thereof L'Oréal (FR) 2007-06-27 EP disclosed
EP-1767191-A1 Makeup kit comprising two cosmetic compositions L'Oréal (FR) 2007-03-28 EP disclosed
EP-1731136-A1 Cosmetic composition containing hollow organosilicon particles L'OREAL (FR) 2006-12-13 EP disclosed
EP-1642620-A1 Hair cosmetic composition comprising hollow particles and silicone fixing polyurethane L'OREAL, S.A. (FR) 2006-04-05 EP disclosed
EP-1642619-A1 Hair cosmetic composition comprising hollow particles and non-silicone fixing polymer L'OREAL (FR) 2006-04-05 EP disclosed
EP-1579841-A1 Cosmetic composition comprising concave particles L'OREAL (FR) 2005-09-28 EP disclosed
EP-1579849-A1 Cosmetic compositions comprising concave particles. L'OREAL (FR) 2005-09-28 EP disclosed
US-20050118218-A1 Emulsion containing organosilicon-based portions of hollow spheres L'OREAL (FR) 2005-06-02 US disclosed
EP-1530961-A2 Emulsion containing hollow organosilicon particles L'OREAL (FR) 2005-05-18 EP disclosed