SCHEMBL1897574

SCHEMBL1897574

CO[SiH2]CCCNC(N)=O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.34
MTNR1A P48039 4/20 0.33
MTNR1B P49286 3/20 0.33
TSHR P16473 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
HIF1A Q16665 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PAOX Q6QHF9 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ACHE P22303 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20468799 0.82 KDM4E (0.54) MTNR1AMTNR1BTSHRKDM4EMAPK1
SCHEMBL1770488 0.81 CA12 (0.34) EPHX1TSHRMEN1KMT2AACHE
SCHEMBL19209504 0.81 MEN1 (0.33) MTNR1AMTNR1BKDM4EMAPK1HIF1A
SCHEMBL23543215 0.80 MEN1 (0.40) TSHRHIF1AMEN1KMT2A
SCHEMBL8513100 0.80 EPHX1 (0.31) EPHX1
SCHEMBL1161353 0.79 ALDH1A1 (0.33) TSHRALDH1A1KMT2A
SCHEMBL28025402 0.79 MAOA (0.37) MEN1KMT2AMAOAMAOB
SCHEMBL728332 0.79 MAOA (0.32) MAOAMAOB
SCHEMBL28483594 0.79 TSHR (0.42) TSHRKDM4EALDH1A1RECQL
SCHEMBL19092275 0.78 MEN1 (0.59) MTNR1AMTNR1BTSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108925298-A A kind of awning film and preparation method thereof that can shorten the crop growth period 东莞市济丰农业生态园开发有限公司 2018-12-04 CN claimed
CN-114460809-A Negative photosensitive resin composition, cured film, display device provided with cured film, and method for producing same 东丽株式会社 2022-05-10 CN disclosed
CN-108885399-B Negative photosensitive resin composition, cured film, display device provided with cured film, and method for producing same 东丽株式会社 2022-03-15 CN disclosed
CN-108604062-B Negative photosensitive resin composition, cured film, display device having cured film, and method for producing same 东丽株式会社 2021-11-09 CN disclosed
CN-110028666-B Polyimide precursor and resin composition containing same 旭化成株式会社 2021-11-09 CN disclosed
CN-111465659-A Coating composition for sealing surfaces 瓦克化学股份公司 2020-07-28 CN disclosed
CN-109089760-A A kind of method that ecologic planting improves greenhouse corps yield 东莞市济丰农业生态园开发有限公司 2018-12-28 CN disclosed
CN-108925298-A A kind of awning film and preparation method thereof that can shorten the crop growth period 东莞市济丰农业生态园开发有限公司 2018-12-04 CN disclosed
US-9303205-B2 Lattice-mismatched core-shell quantum dots EMORY UNIVERSITY (US) 2016-04-05 US disclosed
US-8742061-B2 Polyarylene sulfide film TORAY INDUSTRIES, INC. (JP) 2014-06-03 US disclosed
EP-2501779-A2 LATTICE-MISMATCHED CORE-SHELL QUANTUM DOTS Emory University (US) 2012-09-26 EP disclosed
WO-2011060353-A2 LATTICE-MISMATCHED CORE-SHELL QUANTUM DOTS EMORY UNIVERSITY (US) 2011-05-19 WO disclosed
US-20100143681-A1 FLEXIBLE SUBSTRATE ROHM CO., LTD. (JP) 2010-06-10 US disclosed
US-20090142566-A1 Polyarylene Sulfide Film TORAY INDUSTRIES, INC. (JP) 2009-06-04 US disclosed
US-20090068108-A1 BIOSPECIFIC CONTRAST AGENTS NATIONAL SCIENCE FOUNDATION 2009-03-12 US disclosed
EP-1942149-A1 POLYARYLENE SULFIDE FILM TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed
EP-1487343-A4 BIOSPECIFIC CONTRAST AGENTS UNIV TEXAS (US) 2007-03-21 EP disclosed
EP-1487343-A1 BIOSPECIFIC CONTRAST AGENTS Board of Regents, The University of Texas System (US) 2004-12-22 EP disclosed
US-20040023415-A1 Biospecific contrast agents NATIONAL SCIENCE FOUNDATION 2004-02-05 US disclosed
WO-2003075765-A1 BIOSPECIFIC CONTRAST AGENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2003-09-18 WO disclosed