Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11845012 | 0.88 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL11845006 | 0.88 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL6616923 | 0.87 | PTGS2 (0.40) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL6616919 | 0.87 | PTGS2 (0.40) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL25405954 | 0.83 | MAPT (0.50) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL11614092 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL31236297 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL3257588 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL3257585 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL394821 | 0.82 | VCAM1 (0.41) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087444-A | Amides as ovulation inhibitors | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | disclosed |