Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615227 | 1.00 | NAAA (0.39) | NAAAEP300PDE4DPDE4APDE4B | |
| SCHEMBL11614339 | 0.83 | NAAA (0.35) | NAAA | |
| SCHEMBL14715861 | 0.74 | NAAA (0.34) | NAAAEP300 | |
| SCHEMBL10486020 | 0.74 | NAAA (0.34) | NAAAEP300 | |
| SCHEMBL18974981 | 0.73 | NAAA (0.69) | NAAA | |
| SCHEMBL9806439 | 0.71 | NAAA (0.61) | NAAAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL458567 | 0.70 | ALDH1A1 (0.43) | NAAA | |
| SCHEMBL28862976 | 0.69 | ALDH1A1 (0.42) | NAAAPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL11497336 | 0.69 | EP300 (0.45) | EP300 | |
| SCHEMBL11497335 | 0.69 | EP300 (0.45) | EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117014-A | PROSTAGLANDIN DERIVATIVES | ABBOTT LABORATORIES (US) | 1978-09-26 | — | — | US | disclosed |