Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 5/20 | 0.44 |
| ▸ | IGF1R | P08069 | 4/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9652503 | 0.77 | SMN1; SMN2 (0.70) | ALDH1A1LMNAHSD17B10NPSR1TDP1 | |
| SCHEMBL1945403 | 0.74 | ALDH1A1 (0.55) | ALDH1A1LMNAHSD17B10NPSR1TDP1 | |
| SCHEMBL3472829 | 0.74 | ALDH1A1 (0.55) | ALDH1A1LMNAHSD17B10NPSR1TDP1 | |
| SCHEMBL13143119 | 0.74 | ALDH1A1 (0.55) | ALDH1A1LMNAHSD17B10NPSR1TDP1 | |
| SCHEMBL9375285 | 0.72 | ERCC1 (0.62) | ALDH1A1LMNAHSD17B10NPSR1TDP1 | |
| SCHEMBL14820057 | 0.72 | KMT2A (0.51) | ALDH1A1HSD17B10TDP1HPGDSMN1; SMN2 | |
| SCHEMBL5198556 | 0.72 | NTRK1 (0.72) | ALDH1A1LMNAHSD17B10NPSR1GAA | |
| SCHEMBL9414241 | 0.71 | ALDH1A1 (0.49) | ALDH1A1LMNAHSD17B10NPSR1TDP1 | |
| SCHEMBL3473032 | 0.71 | ALDH1A1 (0.49) | ALDH1A1LMNAHSD17B10NPSR1TDP1 | |
| SCHEMBL14819969 | 0.71 | YTHDF2 (0.47) | ALDH1A1LMNAHSD17B10HPGDKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4105627-A | MERCAPTOHETEROCYCLIC RESIN STABILIZERS | ARGUS CHEMICAL CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |