SCHEMBL9375285

SCHEMBL9375285

O=c1cc(-c2ccccc2)[nH]c(=O)n1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 1/20 0.62
FEN1 P39748 1/20 0.62
ERCC4 Q92889 1/20 0.62
ALDH1A1 P00352 7/20 0.54
LMNA P02545 4/20 0.54
GAA P10253 3/20 0.47
GSK3A P49840 1/20 0.47
GSK3B P49841 1/20 0.47
HSD17B10 Q99714 5/20 0.47
HPGD P15428 4/20 0.47
KDM4C Q9H3R0 1/20 0.47
KDM4E B2RXH2 3/20 0.44
MAPT P10636 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 2/20 0.44
NPC1 O15118 1/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 1/20 0.44
GFER P55789 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9375818 0.78 ALDH1A1 (0.47) ALDH1A1LMNAGAAHSD17B10HPGD
SCHEMBL9652503 0.76 SMN1; SMN2 (0.70) ALDH1A1LMNAGAAGSK3AGSK3B
SCHEMBL1945403 0.76 ALDH1A1 (0.55) ALDH1A1LMNAGAAGSK3AGSK3B
SCHEMBL13143119 0.76 ALDH1A1 (0.55) ALDH1A1LMNAGAAGSK3AGSK3B
SCHEMBL3472829 0.76 ALDH1A1 (0.55) ALDH1A1LMNAGAAGSK3AGSK3B
SCHEMBL1573850 0.73 TSHR (0.50) ALDH1A1LMNAGAAGSK3AGSK3B
SCHEMBL11785182 0.72 ALDH1A1 (0.55) ALDH1A1LMNAHSD17B10HPGDKDM4C
SCHEMBL2065514 0.72 ERCC1 (0.58) ERCC1FEN1ERCC4ALDH1A1LMNA
SCHEMBL11614830 0.72 ALDH1A1 (0.51) ALDH1A1LMNAGAAGSK3AGSK3B
SCHEMBL5322927 0.71 ALDH1A1 (0.47) ERCC1FEN1ERCC4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0438209-B1 Uracil derivatives and pesticides containing the same as active ingredient NISSAN CHEMICAL IND LTD (JP) 1994-09-21 EP disclosed
US-5116404-A URACIL DERIVATIVES AND PESTICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1992-05-26 US disclosed
EP-0438209-A1 Uracil derivatives and pesticides containing the same as active ingredient NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1991-07-24 EP disclosed